Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
The Impact of SNP Score on Low-Density Lipoprotein Cholesterol Concentration and Coronary Artery Disease.
Int J Mol Sci
March 2025
Institute of Cardiology, Lithuanian University of Health Sciences, Sukileliu 15, 50103 Kaunas, Lithuania.
Hypercholesterolemia, characterized by elevated levels of low-density lipoprotein cholesterol (LDL-C), along with inflammation, is a well-known risk factor for developing atherosclerosis and coronary artery disease (CAD). Many patients with hypercholesterolemia may carry inherited genetic variants that are not part of the commonly recognized mutations in the , , , and genes. These genetic variants may have cumulative effects that contribute to increased LDL-C levels and CAD development.
View Article and Find Full Text PDFAssociation of dietary quality indicators with gallstones in the US: NHANES 2017-2020.
BMC Public Health
March 2025
Center of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, No.58 Zhongshan Er Road, Guangzhou, 510080, Guangdong Province, P.R. China.
Background: While dietary factors are known to influence gallstone development, the specific relationships between comprehensive dietary quality indicators and gallstone risk remain poorly understood. This study aimed to explore the association between dietary quality indicators and gallstones using data from the 2017 to 2020 US National Health and Nutrition Examination Survey (NHANES).
Methods: A total of 6,623 US adults were extracted from the 2017-2020 NHANES, of which 734 participants self-reported having gallstones.
Development and validation of an interpretable machine learning model for predicting in-hospital mortality for ischemic stroke patients in ICU.
Int J Med Inform
March 2025
Department of Military Health Statistics, Naval Medical University, Shanghai, China. Electronic address:
Background: Timely and accurate outcome prediction is essential for clinical decision-making for ischemic stroke patients in the intensive care unit (ICU). However, the interpretation and translation of predictive models into clinical applications are equally crucial. This study aims to develop an interpretable machine learning (IML) model that effectively predicts in-hospital mortality for ischemic stroke patients.
View Article and Find Full Text PDFExploring the Intersections between Triglyceride-rich Lipoproteins and Acute Coronary Syndrome: A Cross-sectional Study.
Ann Afr Med
March 2025
Department of General Medicine, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune, Maharashtra, India.
Background: Within 20 years, cardiovascular disease (CVD), which is currently the main cause of death in the Indian subcontinent, is expected to overtake all other causes of death in South Asia. Acute coronary syndrome (ACS), a critical form of CVD, is associated with multiple risk factors including hyperlipidemia. While triglyceride-rich lipoproteins (TRLs) and their remnants are well-studied traditional markers such as low-density lipoprotein (LDL-C) and high-density lipoprotein-cholesterol (HDL-C), new research indicates that they may possibly be important in ACS risk.
View Article and Find Full Text PDFLeveraging circulating DNase I Activity to Detect Silent Coronary Artery Disease among Hypertensive Diabetes Individuals.
Am J Physiol Heart Circ Physiol
March 2025
Department of Biochemistry, AIIMS Raipur, Raipur, Chhattisgarh, India.
In individuals with diabetic hypertension, silent coronary artery disease (CAD) is common due to underlying chronic inflammation but there is no biomarker to monitor this high-risk group of individuals before noticeable symptoms emerge clinically. cfDNA from dying endothelial cells triggers chronic inflammation, leading us to hypothesize that enzymes that degrade cfDNA, DNase I and/or II, could serve as more sensitive biomarkers for silent CAD. To test this, we conducted a study with 30 hypertensive diabetic patients with clinical symptoms of CAD (CAD-HTN-DM) and 30 controls without CAD (HTN-DM).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!