This study aimed to compare the growth performances and carcass characteristics of tropical-breed steers reared in 2 contrasted feeding systems (indoor vs. pasture) and slaughtered at different ages (early vs. late). A total of 309 Creole steers (growing at an initial BW of 173 ± 3 kg and an initial age of 252 ± 4 d) were used over a continuous 12-yr study. Indoor steers were housed in a cattle shed, fed fresh-cut grass plus concentrate, and slaughtered at 14.5 or 17.1 ± 0.1 mo of age. Pasture steers were pasture grazed without supplemental feed, and slaughtered at 17.6 and 21.2 ± 0.1 mo of age. Indoor-fed steers had a greater ADG (786 vs. 517 ± 29 g•d(-1); P < 0.0001) and more carcass fat (164 vs. 145 ± 4.5 g•kg(-1); P = 0.001) than pasture-fed steers. Late-slaughtered steers had decreased ADG (630 vs. 673 ± 27 g•d(-1); P = 0.001) but greater dressing percentages (hot dressing percentage = 55.7 vs. 54.7 ± 0.34%; chilled dressing percentage = 54.5 vs. 53.4 ± 0.34%; P < 0.0001) than early-slaughtered steers. The interaction between feeding system and slaughter age was significant for carcass tissue composition. Whole-carcass muscle content was greater in late-slaughtered steers than early-slaughtered steers, especially in pasture-fed steers (720 vs. 698 ± 6.0 g•kg(-1); P < 0.0001), but less so in indoor-fed steers (707 vs. 700 ± 5.9 g•kg(-1); P = 0.046). Furthermore, increasing slaughter age had no effect on carcass fat in indoor-fed steers (162 vs. 166 ± 4.8 g•kg(-1); P = 0.342), but decreased carcass fat in pasture-fed steers (150 vs. 140 ± 5.0 g•kg(-1); P = 0.014). The results showed that slaughter age and feeding system are 2 major factors that independently affect most of the growth and carcass traits of tropical-breed steers but jointly influence tissue deposition. Our study found that in tropical-breed steers that are grazing, late slaughtering grazing steers increased carcass muscle content without extra fat, thus yielding a carcass quality better suited to consumer choices.
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http://dx.doi.org/10.2527/jas.2012-5999 | DOI Listing |
Histochem Cell Biol
January 2025
Department of Forensic Medicine and Forensic Toxicology, Medical University of Silesia, 18 Medyków Street, 40-752, Katowice, Poland.
Cartilage diseases and injuries are considered difficult to treat owing to the low regenerative capacity of this tissue. Using stem cells (SCs) is one of the potential methods of treating cartilage defects and creating functional cartilage models for transplants. Their ability to proliferate and to generate functional chondrocytes, a natural tissue environment, and extracellular cartilage matrix, makes SCs a new opportunity for patients with articular injuries or incurable diseases, such as osteoarthritis (OA).
View Article and Find Full Text PDFPurpose: To evaluate the effect of osilodrostat and hypercortisolism control on blood pressure (BP) and glycemic control in patients with Cushing's disease.
Methods: Pooled analysis of two Phase III osilodrostat studies (LINC 3 and LINC 4), both comprising a 48-week core phase and an optional open-label extension. Changes from baseline in systolic and diastolic BP (SBP and DBP), fasting plasma glucose (FPG), and glycated hemoglobin (HbA) were evaluated during osilodrostat treatment in patients with/without hypertension or diabetes at baseline.
Nat Commun
January 2025
Fleming Initiative, Institute for Global Health Innovation, Imperial College London, South Kensington Campus, London, UK.
Gut
January 2025
Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, UK
Background: Low-dose amitriptyline, a tricyclic antidepressant (TCA), was superior to placebo for irritable bowel syndrome (IBS) in the AmitripTyline at Low-dose ANd Titrated for Irritable bowel syndrome as Second-line treatment (ATLANTIS) trial.
Objective: To perform post hoc analyses of ATLANTIS for predictors of response to, and tolerability of, a TCA.
Design: ATLANTIS randomised 463 adults with IBS to amitriptyline (232) or placebo (231).
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