Background: Intentional massive sodium chloride ingestions are rare occurrences and are often fatal.
Objectives: There are a variety of treatment recommendations for hypernatremia, ranging from dialysis to varying rates of correction. We report a case of acute severe hypernatremia corrected with rapid free-water infusions that, to our knowledge, has not been previously reported.
Case Report: A 19-year-old man presented to the Emergency Department in a comatose state with seizure-like activity 2 hours after ingesting a quart of soy sauce. He was administered 6 L of free water over 30 min and survived neurologically intact without clinical sequelae. Corrected for hyperglycemia, the patient's peak serum sodium was 196 mmol/L, which, to our knowledge, is the highest documented level in an adult patient to survive an acute sodium ingestion without neurologic deficits.
Conclusion: Emergency physicians should consider rapidly lowering serum sodium with hypotonic intravenous fluids as a potential management strategy for acute severe hypernatremia secondary to massive salt ingestion.
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http://dx.doi.org/10.1016/j.jemermed.2012.11.109 | DOI Listing |
Am J Clin Nutr
January 2025
Slone Epidemiology Center at Boston University, Boston, MA, USA; Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA. Electronic address:
Background: To improve both human health and the health of our planet, the EAT-Lancet Commission proposed the planetary health diet (PHD).
Objective: We aimed to evaluate associations of PHD with all-cause, cardiovascular disease (CVD), and cancer-specific mortality among U.S.
Nutrients
January 2025
National Center for Women and Children's Health, National Health Commission of the People's Republic of China, Beijing 100000, China.
Objective: To investigate the relationship between protein-rich foods, various nutritional supplements, and age of natural menopause and its symptoms.
Methods: This study was a large-scale cross-sectional survey. A multi-stage stratified random sampling method was used to select a sample of 52,347 residents aged 35-60 years from 26 districts/counties across 13 cities in 12 provinces in China.
Foods
January 2025
College of Food and Chemical Engineering, Shaoyang University, Shaoshui Road, Shaoyang 422000, China.
Endogenous peptides in Baijiu have primarily focused on finished liquor research, with limited attention given to the peptides in base liquor prior to blending. Liquid chromatography-tandem mass spectrometry (LC-MS) was employed to identify endogenous peptides in the distillates from the first to seventh rounds of soy sauce-flavored Baijiu. Two hundred and five oligopeptides were identified from these distillates, all of which had molecular weights below 1000 Da and were composed of amino acid residues associated with flavor (sweet, sour, and bitter) and biological activity.
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January 2025
Guangdong Engineering Laboratory of Biomass High-Value Utilization, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences, Guangzhou 510316, China.
Fungi polysaccharides are nutraceutical-rich compounds with bioactive properties, offering promising applications in food formulation. This study examined the non-covalent complexation of commercial polysaccharides derived from the fruiting bodies of (AA) and (GL) and soy protein isolate to enhance emulsifying properties. Complexes were examined across protein-to-polysaccharide ratios (0:1 to 1:0), pH levels (3 to 7), and heat treatment conditions.
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January 2025
College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Deer oil (DO) is a potentially beneficial functional oil; however, its sensitivity to environmental factors (e.g., oxygen and heat), difficulty in transport, and unfavorable taste hinder practical use.
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