High altitude climbing without supplementary oxygen is a common sporting practice and athletes have been extensively evaluated with respect to possible brain functional impairment during its performance. Little is known on the contrary about long-term effects of hypoxia on the central nervous system. We evaluated, at sea level, a group of 10 high-altitude climbers with a battery of neuropsychological tests before and 75 days after the ascent. Our results suggest the occurrence of an impairment of memory performance after return to sea-level at least in some subjects, while speech and certain practical abilities were unchanged.
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http://dx.doi.org/10.1055/s-2007-1024787 | DOI Listing |
Sci Rep
January 2025
Senckenberg Deutsches Entomologisches Institut, Systematik und Biogeographie, Eberswalder Str. 90, 15374, Müncheberg, Germany.
The genus Erebia comprises numerous species in Europe. Due to preference of cold environments, most species have disjunct distributions in the European mountain systems. However, their biogeographical patterns may differ significantly.
View Article and Find Full Text PDFGene
January 2025
ICAR-National Bureau of Animal Genetic Resources Karnal Haryana India. Electronic address:
In this study, whole genome sequence data of Ladakhi cattle from high altitude region of Leh-Ladakh and Sahiwal cattle from arid, semi-arid tropical region were compared. To gain a deeper understanding of the selective footprints in the genomes of Ladakhi and Sahiwal cattle, two strategies namely run of homozygosity (ROH), and fixation index (F) were employed. A total of 975 and 1189 ROH regions were identified in Ladakhi and Sahiwal cattle, respectively.
View Article and Find Full Text PDFPLoS One
January 2025
Division of Neurology, Department of Medicine, The Ottawa Hospital, Ottawa, Ontario, Canada.
Background: Aeromedical transfer of patients with ischemic stroke to access hyperacute stroke treatment is becoming increasingly common. Little is known about how rapid changes of altitude and atmospheric pressure can impact cerebral perfusion and ischemic burden. In patients with ischemic stroke, there is a theoretical possibility that this physiologic response of hypoxia-driven hyperventilation at higher altitude can lead to a relative drop in PaCO2.
View Article and Find Full Text PDFCornea
January 2025
Department of Ophthalmology, Rothschild Foundation, Paris, France; and.
Purpose: The purpose of this study was to investigate the effect of hypoxia and hypobaric conditions on refraction and central corneal thickness on healthy corneas during an ascent without oxygen supplementation above 7000 m (23 000 ft).
Methods: Twelve multinational mountaineers were included in a prospective observational cohort study during an expedition to the Korzhenevskoi Peak (7105 m). The two patients excluded from the study had a history with keratoconus or were current wearers of rigid contact lenses.
Background: Due to the unique geographical and climatic conditions in Nagqu (Tibet), the blood station laboratory was only fully established and accredited by 2020. This study validated the performance of the laboratory's blood screening system and analyzed recent trends in blood donation and screening effectiveness.
Methods: Various serum samples were used to assess the performance of hepatitis B, hepatitis C, HIV, and syphilis tests, both serological and nucleic acid tests.
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