Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3122
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
The integrated study included 184 men aged from 22 to 60 years who were formed into two groups, of the first and second period of middle age. The direct relation of both erectile dysfunction frequency and expressiveness from age was developed. The same dependence was found for hypogonadism clinical features, metabolic syndrome and its components, but inverse relation was detected between age and testosterone content in blood. The presence of erectile dysfunction was associated with testosterone level reduction, hypogonadism clinical features frequency, metabolic syndrome and most its components increase without the age. It was shown that first and second period of middle age men with erectile dysfunction did not display the difference in blood testosterone content, metabolic syndrome and its components frequency. Hence, the main risk factors of erectile dysfunction development form qualitatively already in young men; they accumulate quantitatively with age producing the androgenous disorders evolution.
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