Galectins, a family of glycan-binding proteins, can control tumor progression by promoting transformation, angiogenesis and immune escape. We identified a dynamically regulated 'galectin signature', which delineates the progression of prostate cancer, highlighting galectin-1 as an attractive target for anti-angiogenic therapy in advanced stages of the disease.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654582 | PMC |
| http://dx.doi.org/10.4161/onci.23565 | DOI Listing |
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