A 57-year-old woman presented to the admissions unit with a 2-month history of malaise, chest tightness and non-productive cough. An outpatient chest radiograph arranged by her general practitioner was reported as showing 'changes in keeping with a severe chest infection' and she had been started on oral antibiotics but her clinical condition subsequently deteriorated. On admission she was febrile (39.2°C) and her oxygen saturation was 99% on 60% oxygen via facemask (rapidly desaturating when supplementary oxygen was removed). Auscultation revealed fine mid-late inspiratory crackles over both lung bases. It transpired that 4 months prior to the onset of symptoms she had been started on nitrofurantoin for prophylaxis against urinary tract infections. The nitrofurantoin was stopped and she was started on prednisolone. Her fever and oxygen saturation gradually improved and she was discharged home after 11 days in the hospital. Her improvement was sustained on outpatient review 8 months later.
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http://dx.doi.org/10.1136/bcr-2013-009299 | DOI Listing |
Surg Endosc
January 2025
Clinica Chirurgica, Department of Experimental and Clinical Medicine, Section of Surgical Sciences, Polytechnic University of Marche, Ancona, Italy.
Introduction: Altered vascular microcirculation is recognized as a risk factor for anastomotic leakage (AL) in colorectal surgery. However, few studies evaluated its impact on AL using different devices, with heterogeneous results. The present study reported the initial experience measuring gut microcirculatory density and flow with the aid of incidence dark-field (IDF) videomicroscopy (Cytocam, Braedius, Amsterdam, The Netherlands) comparing its operative outcome using a propensity score matching (PSM) model based on age, gender, and Charlson Comorbidity Index (CCI).
View Article and Find Full Text PDFStem Cell Rev Rep
January 2025
Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Background: The hypobaric hypoxic atmosphere can cause adverse reactions or sickness. The purpose of this study was to explore the preventive effect and mechanism of human umbilical cord mesenchymal stem cells (hUC-MSCs) on acute pathological injury in mice exposed to high-altitude.
Methods: We pretreated C57BL/6 mice with hUC-MSCs via the tail vein injection, and then the mice were subjected to hypobaric hypoxic conditions for five days.
Int J Cardiol
January 2025
Department of Cardiology, Cardiovascular Institute, Thorax Center, Erasmus MC, Rotterdam, the Netherlands; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, the Netherlands.
Background: Little is known about the very long-term outcome in Tetralogy of Fallot (ToF) patients.
Objectives: To prospectively evaluate clinical outcome and quality-of-life after surgical repair of ToF.
Methods: Single-centre, longitudinal cohort-study evaluating every decade 144 ToF patients who underwent surgical repair <15 years of age between 1968 and 1980.
Lasers Med Sci
January 2025
University of Zurich, Zurich, Switzerland.
The aim of this study was to compare the effectiveness of different types of low level laser treatment (LLLT) in reducing pain levels, changing oxygen saturation and bite force in patients with myofacial pain syndrome (MPS). 45 patients were randomly assigned to three groups: Group 1 (GRR laser, n = 15) received LLLT with Gallium-Aluminium-Arsenide (GaAlAs) diode laser with a wavelength of 904 nm and red laser with a wavelength of 650 nm over masseter muscle region. Group 2 (Nd: YAG laser, n = 15) were treated with Neodymium-doped Yttrium Aluminium Garnet laser with a wavelength of 1064 nm and the same protocol with Nd: YAG laser was performed in the Group 3 (placebo, n = 15) using sham device.
View Article and Find Full Text PDFJ Am Heart Assoc
January 2025
Center for Coronary Artery Disease, Division of Cardiology Beijing Anzhen Hospital, Capital Medical University Beijing China.
Background: The circadian rhythm of myocardial infarction (MI) in patients with obstructive sleep apnea (OSA) remains disputable and no studies have directly evaluated the relationship between nocturnal hypoxemia and the circadian rhythm of MI. The aim of the current study was to evaluate the association of OSA and nocturnal hypoxemia with MI onset during the night.
Methods: Patients with MI in the OSA-acute coronary syndrome (ACS) project (NCT03362385) were recruited.
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