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Bedřich Smetana's illness associated with complete hearing loss has been linked to various diseases in a long-running discussion. Senile dementia, atherosclerosis, progressive paralysis in lues are mentioned, while the ototoxicity of mercury is neglected. Its high concentration in the composer's skeletal remains was demonstrated by the authors of this article immunohistochemically and especially by the neutron activation analysis (NAA) method 23 years ago.
View Article and Find Full Text PDFAnalysis of prognosis of neurological sequelae in children with carbon monoxide poisoning.
Sci Rep
December 2024
Department of hyperbaric oxygen and Neurology, the Fourth Affiliated Hospital of Guangxi Medical University, 156 Heping Road, Liuzhou City, 545007, China.
This study retrospectively analyzed children admitted to the Fourth Affiliated Hospital of Guangxi Medical University for CO (carbon monoxide) poisoning from January 2018 to December 2022 and followed up on their neurological sequelae for a long time. The study was approved by the Ethics Committees of the Fourth Affiliated Hospital of Guangxi Medical University (the identification code was KY2023131) and informed consent was obtained from all participants and/or their legal guardians. The study complied with the Declaration of Helsinki.
View Article and Find Full Text PDFBorohydride Hydrolysis Using a Mechanically and Chemically Stable Aluminium-Stainless Steel Porous Monolith Catalyst Made by 3D Printing.
ChemSusChem
October 2024
Van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands.
The challenge of moving to a carbon-free energy economy is highlighted in the context of technology and materials restrictions. Many technologies needed for the so-called energy transition depend on critical metals such as platinum, lithium, iridium and cobalt. Here we focus on solid borohydride salts as hydrogen carriers, studying catalysts for hydrogen release.
View Article and Find Full Text PDFImplementation of a Macroporous Polyhydroxyethylmethacrylate Cryogel-Based Mini-Bioreactor System to Improve Monoclonal Antibody Production.
Front Biosci (Elite Ed)
August 2024
Centre for Bioseparation Technology, Vellore Institute of Technology (VIT), 632014 Vellore, Tamilnadu, India.
Background: Monoclonal antibodies (mAbs) are pioneers in the diagnosis and treatment of many diseases, such as cancer, asthma, poisoning, viral infections, etc. As the market value of mAbs increases in the biopharma industry, the demand for high quantities is met by upscaled production using bioreactor systems. Thus, disposable, porous matrices called cryogels have gained the primary focus for adherent support in the proliferation of hybridoma cells.
View Article and Find Full Text PDFHigh-intensity interval training alleviates liver inflammation by regulating the TLR4/NF-κB signaling pathway and M1/M2 macrophage balance in female rats with cisplatin hepatotoxicity.
Biochem Biophys Res Commun
November 2024
Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Vitória da Conquista, Bahia, 45029-094, Brazil. Electronic address:
Cisplatin (CDDP) is an antineoplastic drug whose adverse effects include hepatotoxicity. The inflammatory process is crucial in the progression of liver injuries. Exercise is known for its anti-inflammatory effects, but the influence of different training modalities on hepatoprotection is still unclear.
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