Tumor suppression by p53: is apoptosis important or not?

Cell Rep

Howard Hughes Medical Institute and Department of Molecular, Cellular, and Developmental Biology, University of Colorado at Boulder, Boulder, CO 80309, USA.

Published: May 2013

The mechanisms by which p53 suppresses tumor growth remain ill defined. In this issue of Cell Reports, Timofeev et al. (2013) and Valente et al. (2013) reveal context-dependent contributions of p53-dependent apoptosis to its tumor-suppressive function.

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Source
http://dx.doi.org/10.1016/j.celrep.2013.05.011DOI Listing

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