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Chip-scale fluorescence microscope based on a silo-filter complementary metal-oxide semiconductor image sensor. | LitMetric

We demonstrate a silo-filter (SF) complementary metal-oxide semiconductor (CMOS) image sensor for a chip-scale fluorescence microscope. The extruded pixel design with metal walls between neighboring pixels guides fluorescence emission through the thick absorptive filter to the photodiode of a pixel. Our prototype device achieves 13 μm resolution over a wide field of view (4.8 mm × 4.4 mm). We demonstrate bright-field and fluorescence longitudinal imaging of living cells in a compact, low-cost configuration.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740726PMC
http://dx.doi.org/10.1364/OL.38.001817DOI Listing

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