AI Article Synopsis
- Del(5)(q) is a chromosomal abnormality often linked to a good prognosis in Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML), but its role in Acute Lymphoblastic Leukemia (ALL) is not well understood.
- A case study is presented involving a 75-year-old adult patient diagnosed with ALL, featuring the specific cytogenetic abnormality del(5)(q32).
- The patient's clinical characteristics, cell morphology, and immunophenotyping indicated a diagnosis of T-cell Acute Lymphoblastic Leukemia (T-ALL), with further relevant literature reviewed for context.
Article Abstract
Del(5)(q) is a common chromosomal abnormality with favourable prognosis in Myelodysplastic Syndrome (MDS) and Acute myeloid leukemia (AML). However, del(5)(q) is also seen rarely in Acute lymphoblastic leukemia (ALL) and its significance remains poorly understood. We present here, a case report of diagnosis of an adult 75 year old patient of ALL with a cytogenetic abnormality of del(5)(q32). His clinical features, morphology and immunophenotyping findings were suggestive of T-ALL. Relevant literature has been reviewed and discussed.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656527 | PMC |
| http://dx.doi.org/10.4103/0971-6866.108028 | DOI Listing |
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