Treatment results of 368 patients with infected pancreonecrosis were analyzed. Overall lethality was 29.6 ± 3.4%. Maximal lethality was among patients with phlegmona - 43.6 ± 5%, minimal (12.9 ± 3.8%) among patients with abscess. Spread phlegmonas, when closed sequestrectomy was impossible, were treated by transversal omentobursopancreatostomy. When the closed drainage of infected pancreonecrosis areas was not effective after 10-13 days, conversion to the omentobursopancreatostomy was performed. Lethality among patients with non-alternative closed drainage was 50.0 ± 4.5%. Lethality after omentobursopancreatostomy was 19.0 ± 4.2%.
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Khirurgiia (Mosk)
January 2024
Penza State University, Penza, Russia.
Objective: Based on objective criteria of the structural and functional state of the kidneys in various urgent surgical and uronephrological pathologies (peritonitis, pancreonecrosis, intestinal obstruction, urinary peritonitis, acute purulent secondary pyelonephritis) to identify and prove the general pattern of development of renal changes, their influence on the pathogenesis of homeostasis disorders at the organizational level and to form the evidence base of a new symptom complex - renal distress syndrome in surgery and uronephrology; to establish the effectiveness of Remaxol in its correction.
Material And Methods: Experimentally on 60 mongrel dogs with acute peritonitis, pancreatitis, intestinal obstruction of varying severity, the state of renal function, including detoxification, was assessed based on the assessment of the inflow-outflow difference in the level of toxins and in the parenchyma of organs - the composition of lipids, the activity of peroxidation of membrane lipids and phospholipases. Clinical and laboratory studies included patients with acute peritonitis (48), acute pancreatitis (18), intestinal obstruction (21), acute purulent secondary pyelonephritis (19).
Khirurgiia (Mosk)
May 2021
Samara City Hospital No. 10, Samara, Russia.
Unlabelled: Severe acute pancreatitis is one of the most difficult problems in emergency abdominal surgery. Mortality among patients with this disease ranges from 20 to 80 percent. The use of staged surgical intervention in the treatment of purulent complications of acute severe pancreatitis may affect not only the risk of open surgery, but also the number of post-operative complications.
View Article and Find Full Text PDFKhirurgiia (Mosk)
December 2020
A.I. Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia.
Objective: To analyze the results of pancreatic duct stenting in moderate and severe forms of pancreatitis.
Material And Methods: Pancreatic duct stenting in 300 patients with acute pancreatitis was analyzed. Examination and treatment were carried out in accordance with national clinical guidelines for acute pancreatitis (2015).
Hematol Oncol Stem Cell Ther
September 2019
Raisa Gorbacheva Memorial Research Institute of Children Oncology, Hematology and Transplantation, Department of Hematology, Transfusiology, Transplantation, Faculty of Postgraduate Education, Pavlov First Saint Petersburg State Medical University, Saint-Petersburg, Russia.
Background: Allogeneic hematopoietic stem cell transplantation (alloHSCT) is the only treatment option with curative potential in patients with myelofibrosis (MF). The aim of our study was to evaluate the safety of splenectomy before alloHSCT in MF patients who failed to achieve significant spleen response after ruxolitinib therapy.
Methods: Splenectomy was performed in 12 patients for alloHSCT with myelofibrosis-primary (6 patients), post-polycythemia vera (3 patients).
The results of miniinvasive transcutaneous interventions for purulent—septic complications of pancreonecrosis are presented. The computeric tomography (CT) and the ultrasound investigation data where compared while choosing of transcutaneous access towards purulent focus. Peculiar attention was drawn to searching of extraperitoneal trajectory for the drain conduction way.
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