Background: The silicone granuloma was first described in the literature in 1964. During the course of clinical practice, the plastic surgeon will encounter a silicone granuloma in a breast augmentation or reconstruction patient. This review addresses the clinical significance associated with silicone granulomas. Clinical implications and indications for intervention are discussed, and a reasonable management algorithm is proposed.
Methods: A review of the literature relating to silicone granulomas and their clinical implications was performed.
Results: Although case series have been reported, there is no consensus regarding the treatment of silicone granulomas.
Conclusions: This important clinical entity warrants investigative attention to better understand its clinical implications and prevention. An algorithm for treatment is proposed.
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http://dx.doi.org/10.1097/PRS.0b013e31828bd642 | DOI Listing |
Int J Dermatol
January 2025
Department of Dermatology, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
BMJ Case Rep
January 2025
General Surgery, Universidade de Lisboa Faculdade de Medicina, Lisboa, Portugal.
We report a case of a woman in her late 40s with a history of breast implant surgery following breast cancer treatment. She presented with asymmetrical breast enlargement, palpable contralateral axillary lymph nodes and cutaneous nodules on both forearms. In addition, imaging evaluation revealed intracapsular implant rupture, ipsilateral internal mammary enlarged lymph nodes and multiple mediastinal lymphadenopathies.
View Article and Find Full Text PDFPathol Int
October 2024
Department of Pathology, Toyama Prefectural Central Hospital, Toyama, Japan.
Ann Pathol
November 2024
Cabinet Mathurin Moreau/Xpath, Paris, France; Service de pathologie de Cochin, hôpital Cochin, Paris, France. Electronic address:
Any product injected to fill wrinkles can behave like a foreign body and cause unsightly granulomatous reactions. The subject is constantly evolving, subject to the vagaries of the market. Hyaluronic acid is the most injected product because it is resorbable and probably the least "toxic".
View Article and Find Full Text PDFAm J Dermatopathol
December 2024
Department of Dermatology, Dermatopathology and Oral Pathology Unit, University of California, San Francisco, CA.
Silicone granulomas, or "siliconomas," are the common foreign-body inflammatory responses to injected silicone material. In rare cases, siliconomas develop remotely from the original site of injection, secondary to silicone migration. If a history of silicone injection is not noted, such lesions risk misdiagnosis (possibly as infection or malignancy).
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