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http://dx.doi.org/10.1016/j.bpj.2013.04.010 | DOI Listing |
Carbohydr Polym
January 2025
Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Kemivägen 10, Gothenburg 41296, Sweden; Department of Bioproducts and Biosystems, Aalto University, Vuorimiehentie 1, Aalto FI-00076, Finland. Electronic address:
Bio-based compounds have become the focus in the development of next-generation materials. The polyphosphated structure and availability of phytic acid has sparked an interest to understand its properties and apply it to making fire-retardant fabrics. However, its degradative effect on natural fibers sets limitations to its potential uses.
View Article and Find Full Text PDFInt J Psychiatry Med
July 2024
Advocate Illinois Masonic Medical Center, Chicago, IL, USA.
The unrelenting turmoil of the COVID-19 pandemic has been especially hard on those in the healthcare field. This chronic stress has resulted in depleted compassion towards patients served and colleagues. Researchers have suggested that empathy is a finite resource that must be replenished.
View Article and Find Full Text PDFJAMA Ophthalmol
March 2023
Nuffield Laboratory of Ophthalmology, Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.
Importance: X-linked retinitis pigmentosa (XLRP) is a severe cause of early-onset RP in male individuals, characterized by degeneration of photoreceptors, an extinguished electroretinogram, and vision loss.
Objective: To assess the duration of improvements in retinal sensitivity associated with a single, subretinal injection of cotoretigene toliparvovec (BIIB112/AAV8-RPGR) gene therapy after vitrectomy surgery in the dosed eye over 12 months in part 1 of the Clinical Trial of Retinal Gene Therapy for X-linked Retinitis Pigmentosa Using BIIB112 (XIRIUS) study, compared with untreated fellow eyes and eyes from the untreated subgroup from the Natural History of the Progression of X-Linked Retinitis Pigmentosa (XOLARIS) study.
Design, Setting, And Participants: This was a post hoc analysis of the XIRIUS and XOLARIS studies.
Behav Pharmacol
April 2023
Institute of Neuroscience, Medical School, Newcastle University, Newcastle upon Tyne, UK.
Mitragynine (MG) is a pharmacologically active alkaloid derived from the leaves of Mitragyna speciosa Korth (Kratom). This plant has sparked significant interest as a potential alternative treatment for managing opioid dependence and withdrawal due to its opioid-like pharmacological effects. However, whether MG exposure would trigger opioid-seeking behaviour following abstinence has not been investigated.
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