Infective endocarditis (IM) of the artificial cardiac valve (ACV) constitutes one of severe postoperative complications and presents a total spectrum and number of observations, concerning infectioning of the implanted ACV or of the adjacent tissues, which have had occurred in various time postoperatively. Wide introduction in practical cardiosurgery have caused the raising of the IM of ACV occurrence rate from 16 to 45%. Basing on analysis of data of 276 patients there were studied up the factors and conditions, predisposing to occurrence of IM in ACV. The main causes of a primary affection of natural cardiac valves in the patients were rheumatism and IM, the leading role in occurrence of bacteriemia have played nosocomial factors while performing stomatological, urological, gynecological and general surgical manipulations.

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