AI Article Synopsis
- * Salimabromide, a natural product isolated from the marine myxobacteria, features a unique tetracyclic carbon structure that includes a brominated benzene ring and a cyclohexane ring.
- * This compound demonstrates antibiotic properties specifically against the bacteria Arthrobacter cristallopoietes.
Article Abstract
Marine myxobacteria (Enhygromyxa, Plesiocystis, Pseudoenhygromyxa, Haliangium) are phylogenetically distant from their terrestrial counterparts. Salimabromide is the first natural product from the Plesiocystis/Enhygromyxa clade of obligatory marine myxobacteria. Salimabromide has a new tetracyclic carbon skeleton, comprising a brominated benzene ring, a furano lactone residue, and a cyclohexane ring, bridged by a seven-membered cyclic moiety. The absolute configuration was deduced from experimental and calculated CD data. Salimabromide revealed antibiotic activity towards Arthrobacter cristallopoietes.
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| http://dx.doi.org/10.1002/chem.201301379 | DOI Listing |
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