Species selective diazirine positioning in tag-free photoactive quorum sensing probes.

Chem Commun (Camb)

Department of Chemistry and the National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Be'er-Sheva 84105, Israel.

Published: July 2013

The synthesis and comparison of activities of 'tag-free' probes with diazirines at various positions are described. Remarkable differences in their effects on P. aeruginosa and on human bronchial epithelial cells were observed, supporting the efforts to isolate and identify receptors for N-acyl homoserine lactones.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723129PMC
http://dx.doi.org/10.1039/c3cc43092hDOI Listing

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