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Three-component assembly of structurally diverse 2-aminopyrimidine-5-carbonitriles. | LitMetric
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Three-component assembly of structurally diverse 2-aminopyrimidine-5-carbonitriles.

Cristina Val Abel Crespo Vicente Yaziji Alberto Coelho Jhonny Azuaje Abdelaziz El Maatougui Carlos Carbajales Eddy Sotelo

ACS Comb Sci

Center for Research in Biological Chemistry and Molecular Materials (CIQUS) and ‡Department of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, Santiago de Compostela, 15782, Spain.

Published: July 2013

An expedient route for the synthesis of libraries of diversely decorated 2-aminopyrimidine-5-carbonitriles is reported. This approach is based on a three-component reaction followed by spontaneous aromatization.

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 Source
http://dx.doi.org/10.1021/co4000503DOI Listing

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