Epilepsy, which is based on etiology and is categorized as either primary or secondary, is diagnosed in patients who have experienced multiple seizures over weeks or months. This article discusses the etiology of epilepsy as well as the prevalence of epilepsy in canines, which has been reported to be between one and three percent. A case report is included, which involves a three-year-old, 143-pound, male intact mastiff who presented to Mississippi State University College of Veterinary Medicine with an acute onset of seizure activity.

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