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A New Generation of Postbiotics for Skin and Scalp: In Situ Production of Lipid Metabolites by .
Microorganisms
August 2024
DSM-Firmenich, Perfumery & Beauty, Wurmisweg 576, CH-4303 Kaiseraugst, Switzerland.
Effects of pre- and probiotics on intestinal health are well researched and microbiome-targeting solutions are commercially available. Even though a trend to appreciate the presence of certain microbes on the skin is seeing an increase in momentum, our understanding is limited as to whether the utilization of skin-resident microbes for beneficial effects holds the same potential as the targeted manipulation of the gut microflora. Here, we present a selection of molecular mechanisms of cross-communication between human skin and the skin microbial community and the impact of these interactions on the host's cutaneous health with implications for the development of skin cosmetic and therapeutic solutions.
View Article and Find Full Text PDFPediatric Dermatitis Seborrhoica - A Clinical and Therapeutic Review.
Indian Dermatol Online J
April 2024
Department of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital, Dresden, Germany.
Pediatric dermatitis seborrhoica (DS) is a common inflammatory disorder of infancy and adolescence distinct from atopic dermatitis. We performed a narrative review on clinical and therapeutic aspects of the disease. The prevalence varies geographically and can reach up to 10%.
View Article and Find Full Text PDFRegulatory Ability of on Human Skin Health by Counteracting In Vitro Effects.
J Fungi (Basel)
November 2023
Department of Mental and Physical Health and Preventive Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
The skin serves as the first barrier against pathogen attacks, thanks to its multifunctional microbial community. is a commensal organism of normal cutaneous microflora but is also a cause of skin diseases. It acts on different cell pattern recognition receptors (TLRs, AhR, NLRP3 inflammasome) leading to cellular damage, barrier impairment, and inflammatory cytokines production.
View Article and Find Full Text PDFPart 2: Understanding the role of spp. in skin disorders: pathogenesis of associated skin infections.
Expert Rev Anti Infect Ther
November 2023
Department of Veterinary Medicine, University of Bari Aldo Moro, Valenzano, Italy.
Introduction: is a major component of the skin microbiome, a lipophilic symbiotic organism of the mammalian skin, which can switch to opportunistic pathogens triggering multiple dermatological disorders in humans and animals. This phenomenon is favored by endogenous and exogenous host predisposing factors, which may switch from a commensal to a pathogenic phenotype.
Area Covered: This review summarizes and discusses the most recent literature on the pathogenesis of yeasts, which ultimately results in skin disorders with different clinical presentation.
Assessment of a novel continuous cleaning device using metatranscriptomics in diverse hospital environments.
Front Med Technol
March 2023
Contamination Source Identification, LLC., Huntingdon, PA, United States.
Article Synopsis
- The study highlights the challenge of pathogen transmission from contaminated surfaces in healthcare settings, even with regular cleaning protocols.
- Researchers analyzed high-touch surfaces using advanced sequencing techniques to evaluate the effectiveness of cleanSURFACES® technology in reducing microbial contamination in an Emergency Department and an Oncology Ward during the COVID-19 pandemic.
- Results showed that while overall microbial richness remained unchanged, the composition of microbial communities shifted significantly post-intervention, indicating that cleanSURFACES® combined with routine disinfection can improve surface hygiene in hospitals.
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