Ancient neurilemoma is a rare variant of neurilemoma and can grow into a large tumor, which results in several symptoms. It is often misdiagnosed to be malignant neoplasm because of its histological features of nuclear atypia. The authors reported an 87-year-old woman presenting with progressive dyspnea and chronic cough for more than 1 year. Computed tomography of the chest showed a huge heterogeneous, paravertebral mass with focal calcification, arising from intervertebral foramen. The tumor was successfully resected by thoracotomy and pathology disclosed ancient neurilemoma.
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Ancient schwannoma of the submandibular gland.
BMJ Case Rep
January 2025
Division of Plastic and Reconstructive Surgery, Department of Surgery, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand
Schwannomas, benign tumours derived from Schwann cells, exhibit slow growth rates and are commonly found extracranially in the head, neck and extremities. However, intraoral and salivary gland schwannomas are less frequent. Ancient schwannomas, characterised by histological degenerative changes, represent a rare variant.
View Article and Find Full Text PDFComprehensive study of ancient schwannoma: Exploring histomorphological diversity and diagnostic challenges.
Rare Tumors
September 2024
Department of Pathology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Karnataka, Manipal, India.
Article Synopsis
- * A study analyzed 248 schwannoma cases over six years, with 25 identified as ancient schwannoma, evaluating their histological features through light microscopy.
- * The findings revealed significant features like nuclear atypia and cystic changes in tumors from various locations, highlighting the need for careful histomorphological assessment to correctly diagnose and manage these tumors.
Clinical and radiological features of intracranial ancient schwannomas: a single-institution, retrospective analysis.
Brain Tumor Pathol
April 2024
Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Article Synopsis
- Ancient schwannoma (AS) is a benign subtype of schwannoma that displays unique clinical features compared to conventional schwannomas, especially in the intracranial region.
- A study of 174 patients revealed that 7.5% had AS, which was significantly associated with higher rates of cyst formation, bleeding, and larger tumor sizes compared to other types of schwannoma.
- Despite these differences, both groups had similar symptom onset to surgery durations and postoperative recurrence rates, indicating that intracranial AS may not follow the slow progression seen in extracranial AS cases.
Huge mediastinal ancient schwannoma causing acute respiratory failure: a case report.
J Cardiothorac Surg
March 2024
Department of Thoracic and Cardiovascular Surgery, Kaohsiung Chang Gung Memorial Hospital, 123, Tapei Rd., Niaosung District, Kaohsiung City, 833, Taiwan, ROC.
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- Benign mediastinal tumors are generally asymptomatic but can occasionally cause severe issues, as seen in a case involving a huge posterior mediastinal schwannoma that led to respiratory failure.
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Ancient schwannoma of the thoracic spine treated with vertebroplasty: A case report.
Int J Surg Case Rep
March 2024
Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Introduction: Intraosseous schwannomas or neurilemomas are rare benign neoplasms. Total resection of the intraosseous schwannoma is considered risky in immunocompromised patients, thus minimally invasive vertebroplasty was conducted in this study.
Case Report: In this case, we presented A 40-year-old male presented with intermittent back pain for the last two years.
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