[Causes of in utero fetal deaths: 225 cases at Befelatanana Hospital, Madagascar].

Med Sante Trop

Faculté de médecine d'Antananarivo, Antananarivo, Madagascar, Faculté de médecine Jules Vernes, Amiens, France.

Published: March 2014

Introduction: The high rate of in utero fetal death in our hospital led us to study its risk factors and causes.

Methods: We conducted a case-control study from 1 January to 30 June, 2011, of all fetal deaths in utero in the Gynecology-Obstetrics University Hospital of Befelatanana. Risk factors were studied after comparison with a random sample of live births during the same period. The causes were classified according to the Perinatal Death Classification of the Perinatal Society of Australia and New Zealand.

Results: The rate of in utero fetal deaths was 5.22%. The risk factors statistically verified were: mother older than 34 years, parity of five or more, preterm, fewer than four prenatal consultations, previous fetal loss or hypertension disorders, and mother working in agriculture or commerce. The causes identified were hypertensive disorders (20.66%), prepartum hemorrhage (18.18%), fetal growth restriction (14.87%), premature rupture of the membrane (14.05%), hypoxia (12.39%), perinatal infection (11.57%), maternal conditions (3.30%), congenital abnormalities (3.30%), and specific perinatal conditions (1.65%).

Conclusion: Screening for risk factors and close monitoring during pregnancy and labor are important to reduce fetal deaths.

Download full-text PDF

Source
http://dx.doi.org/10.1684/mst.2013.0143DOI Listing

Publication Analysis

Top Keywords

fetal deaths
16
risk factors
16
utero fetal
12
rate utero
8
fetal
7
[causes utero
4
deaths
4
deaths 225
4
225 cases
4
cases befelatanana
4

Similar Publications

Background: Cardiovascular disease (CVD) remains the leading cause of death in pregnant and peripartal women in western countries. Physiological changes during pregnancy can lead to cardiovascular complications in the mother; women with pre-existing heart disease may not tolerate these changes well, increasing their susceptibility to adverse cardiovascular outcomes during pregnancy. The aim of this study is to characterize pregnancy-induced changes in cardiac function, biomarker concentrations and cardiovascular outcomes in women with CVD during pregnancy at a tertiary care hospital in Germany.

View Article and Find Full Text PDF

Graft ischemia post cell transplantation to the brain: Glucose deprivation as the primary driver of rapid cell death.

Neurotherapeutics

January 2025

School of Pharmacy and Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, Cardiff, CF10 3NB, UK; Leibniz-Institut für Polymerforschung Dresden, Max Bergmann Center of Biomaterials Dresden, Hohe Straße 6, D-01069 Dresden, Germany. Electronic address:

Replacing cells lost during the progression of neurodegenerative disorders holds potential as a therapeutic strategy. Unfortunately, the majority of cells die post-transplantation, which creates logistical and biological challenges for cell therapy approaches. The cause of cell death is likely to be multifactorial in nature but has previously been correlated with hypoxia in the graft core.

View Article and Find Full Text PDF

Objective: In the UK and worldwide, there are substantial ethnic inequalities in maternal and perinatal care and outcomes. We aim to assess the impact of the unprecedented change in care provision during the COVID-19 pandemic on inequalities in adverse maternity outcomes.

Design: Retrospective cohort study using structured electronic health record data.

View Article and Find Full Text PDF

Background: Despite strong evidence-based strategies for prevention and management, global efforts to reduce deaths from postpartum haemorrhage (PPH) have failed, and it remains the leading cause of maternal mortality. We conducted a detailed review of all maternal deaths from 33 facilities in Malawi to identify health system weaknesses leading to deaths from PPH.

Methods: Data were collected regarding every maternal death occurring across all district and central hospitals in Malawi.

View Article and Find Full Text PDF

Longitudinal Twin Growth Discordance Patterns and Adverse Perinatal Outcomes.

Am J Obstet Gynecol

January 2025

Fetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, London, United Kingdom; Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's University of London, London, United Kingdom; Twin and Multiple Pregnancy Centre for Research and Clinical Excellence, St George's University Hospital, St George's University of London, London, UK; Fetal Medicine Unit, Liverpool Women's Hospital, Liverpool, United Kingdom. Electronic address:

Objective: The objective of this study was to conduct a longitudinal assessment of inter-twin growth and Doppler discordance, to identify possible distinct patterns, and to investigate the predictive value of longitudinal discordance patterns for adverse perinatal outcomes in twin pregnancies.

Methods: This retrospective cohort study included twin pregnancies followed and delivered at a tertiary University Hospital in London (UK), between 2010 and 2023. We included pregnancies with at least three ultrasound assessments after 18 weeks and delivery after 34 weeks' gestation.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!