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Hyperkaliaemic cardiac arrest in Angelman's syndrome following suxamethonium.
BMJ Case Rep
December 2024
Critical Care, North West Anglia NHS Foundation Trust, Peterborough, UK.
We present a case of hyperkaliaemic cardiac arrest in a patient with Angelman's syndrome after administration of suxamethonium in rapid sequence intubation. The patient was admitted to the critical care unit in with aspiration pneumonia and intestinal obstruction. They had a cardiac arrest after suxamethonium administration.
View Article and Find Full Text PDFIL-35 may prevent the exacerbation of aspiration pneumonia involving Porphyromonas gingivalis by suppressing IL-17 production.
Am J Pathol
December 2024
Department of Periodontology, School of Dentistry, Aichi Gakuin University, Nagoya, Japan.
Periodontitis was reported to be associated with aspiration pneumonia. However, the relationship between periodontitis and aspiration pneumonia remains unclear. This study investigated the virulence factor of Porphyromonas gingivalis, which exacerbates aspiration pneumonia, and the role of IL-35, an inhibitory heterodimeric cytokine of EBI3 and p35, in aspiration pneumonia using Ebi3 knockout (KO) mice.
View Article and Find Full Text PDFImpact of COVID-19 pandemic on pneumonia trends in Japan: Insights from diagnosis procedure combination data.
Respir Investig
December 2024
Department of Rehabilitation for Orofacial Disorders, Osaka University Graduate School of Dentistry, Osaka, 565-0871, Japan.
This study analyzed changes in pneumonia hospitalizations in Japan before and after the COVID-19 pandemic using Diagnosis Procedure Combination data. The proportion of inpatients with non-aspiration pneumonia (non-AP) decreased by 48.8%, whereas that of inpatients with aspiration pneumonia (AP) decreased by only 8.
View Article and Find Full Text PDFEvaluation of Different Sampling Methods Combined with Metagenomic Next-Generation Sequencing of Respiratory Specimens in Etiological Diagnosis of Patients with Severe Pneumonia.
Infect Drug Resist
December 2024
Department of Clinical Microbiology Laboratory, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, People's Republic of China.
Objective: To evaluate the value of respiratory specimens collected via different sampling methods combined with metagenomic next-generation sequencing (mNGS) in the etiological diagnosis of severe pneumonia.
Methods: A total of 117 patients with severe pneumonia between 2019 and 2024 were included in this study, with 60 patients undergoing endotracheal aspiration (ETA) and 57 undergoing bronchoalveolar lavage (BAL), respectively. Patient records were retrospectively reviewed.
Case report: Identification of a Chinese patient with mutations initially presenting as autoimmune hemolytic anemia.
Front Immunol
December 2024
Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, China.
Mutations in the recombination-activating gene 1, a pivotal component essential for V(D)J recombination and the formation of T- and B-cell receptors, can result in autoimmune hemolytic anemia, a rare hematological condition characterized by the autoantibody-mediated destruction of red blood cells. Herein, we report the case of a 1-year-and-4-month-old girl who presented with progressively aggravated anemia, fever, and cough. Autoimmune hemolytic anemia was confirmed by bone marrow aspiration and Coombs test.
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