Scapholunate ligament disruptions and scaphoid nonunions are known to follow predictable patterns of arthritis. Advanced cases of such degenerative arthritis have traditionally been treated by either 4-corner fusion or proximal row carpectomy. Four-corner fusion has relied on the surface area provided by the capitate, lunate, triquetrum, and hamate to achieve a union. Earlier attempts in decreasing the involved surface area, that is, through fusion of only the capitolunate joint were not met with great success. With the advent of compression screws, however, we feel it is possible to achieve union while incorporating less surface area into the fusion block. We propose a novel procedure, the "2-corner, 3-carpal" fusion, which fuses only the capitate, lunate, and triquetrum, excluding the hamate. By taking advantage of compression screw technology we were able to achieve union and acceptable range of motion in 10 patients in our institution who underwent this procedure.
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http://dx.doi.org/10.1097/BTH.0b013e31828d6070 | DOI Listing |
Background: Ruxolitinib cream has demonstrated anti-inflammatory and antipruritic activity and was well tolerated in a phase 3 study in patients aged 2-11 years with mild to moderate atopic dermatitis (AD).
Objective: This study examined the safety, tolerability, pharmacokinetics, efficacy, and quality of life (QoL) with ruxolitinib cream under maximum-use conditions and with longer-term use.
Methods: Eligible patients were aged 2-11 years with moderate to severe AD [Investigator's Global Assessment (IGA) score 3-4], and ≥ 35% affected body surface area (BSA).
Int J Implant Dent
January 2025
Lecturer at removable prosthodontic department, Faculty of dental medicine for Girls, Al-Azhar University, Cairo, Egypt.
Purpose: In this randomized clinical trial, we examined the incorporation of nanogold particles into polymethyl methacrylate denture bases and compared these modified bases with conventional ones in mandibular implant-retained overdentures, focusing on microbiological growth and adhesion characteristics.
Methods: In this study, twenty-two male patients who were completely edentulous participated in a rehabilitation program involving mandibular overdentures retained by two dental implants placed in the canine area. The subjects were categorized into two equal groups, each comprising eleven patients.
Rev Med Chil
July 2024
Departamento de Nefrología, Escuela de Medicina, Facultad de Medicina, Universidad Católica de Chile, Santiago, Chile.
Unlabelled: Glomerular filtration rate estimates are usually indexed to a standard body surface area (BSA) of 1.73 m2. This allows comparing values of individuals of different sizes but has the potential of affecting individuals with extremes BSA.
View Article and Find Full Text PDFJ Am Chem Soc
January 2025
Center for Nanomedicine, Institute for Basic Science (IBS), Seoul 03722, Republic of Korea.
Perpendicular nanochannel creation of two-dimensional (2D) nanostructures requires highly controlled anisotropic drilling processes of the entire structure via void formation. However, chemical approaches for the creation of porosity and defects of 2D nanostructures have been challenging due to the strong basal plane chemical stability and the use of harsh reactants, tending to give randomly corroded 2D structures. In this study, we introduce Lewis acid-base conjugates (LABCs) as molecular drillers with attenuated chemical reactivity which results in the well-defined perpendicular nanochannel formation of 2D TiS nanoplates.
View Article and Find Full Text PDFSmall
January 2025
KU-KIST Graduate School of Converging Science and Technology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.
Non-layered 2D materials offer unique and more advantageous physicochemical properties than those of conventional 2D layered materials. However, the isotropic chemical bonding nature of non-layered materials hinders their lateral growth, making the synthesis of large-area continuous thin films challenging. Herein, a facile kinetically tailored chemical vapor deposition (KT-CVD) approach is introduced for the synthesis of 2D molybdenum nitride (MoN), a representative non-layered material.
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