A novel luminescent biscyclometalated iridium(III) complex [Ir(C^N)2bpy]PF6 (Ir-S, bpy = 2,2'-bipyridine) containing two 2-phenylpyridine (ppy) cyclometalating ligands (C^N) functionalized with 1,3-dithiane for the detection of Hg(2+) ions has been synthesized and characterized by spectroscopic and photophysical measurements. The luminescence of Ir-S exhibits a ratiometric response upon the addition of Hg(2+) ions. The absorption, emission, (1)H NMR and ESI mass spectral changes of Ir-S in the absence and presence of Hg(2+) ions have all demonstrated the Hg(2+)-promoted thioacetal deprotection reaction of Ir-S and the generation of a complex [Ir(pba)2bpy]PF6 (Ir-CHO, Hpba = 4-(pyridin-2-yl)benzaldehyde). DFT calculation studies suggest that the dominant participation of the 1,3-dithiane group in the HOMO of Ir-S leads to different excited states and distinct excited energies of Ir-S and Ir-CHO and consequently results in their different emission properties. The titration and competition experiments significantly reveal the highly sensitive and selective properties of Ir-S as a promising indicator for Hg(2+) ions over other metal cations.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c3dt50807b | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Predicting the location of coordinated metal ion-ligand binding sites using geometry-aware graph neural networks.
Comput Struct Biotechnol J
December 2024
Department of Electrical Engineering and Computer Science, Bond Life Sciences Center, University of Missouri, Columbia, MO, USA.
More than 50 % of proteins bind to metal ions. Interactions between metal ions and proteins, especially coordinated interactions, are essential for biological functions, such as maintaining protein structure and signal transport. Physiological metal-ion binding prediction is pivotal for both elucidating the biological functions of proteins and for the design of new drugs.
View Article and Find Full Text PDFSimultaneous or separate detection of heavy metal ions Hg and Ag based on lateral flow assays.
Mikrochim Acta
January 2025
Department of General Surgery, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, 266035, China.
A lateral flow assay (LFA) was developed for the simultaneous or separate detection of mercury ion and silver ion based on isothermal nucleic acid amplification. T-Hg-T and C-Ag-C were utilized in the isothermal nucleic acid amplification strategy to form specific complementary base pairs. Under the action of KF polymerase and endonuclease Nt.
View Article and Find Full Text PDFDual-mode ratiometric fluorescent and colorimetric sensor for rapid visual detection of Hg using poly(T)-tailed ssDNA-silver nanoclusters.
Spectrochim Acta A Mol Biomol Spectrosc
January 2025
College of Chemistry and Environmental Engineering, Sichuan University of Science and Engineering, Zigong 643000 PR China. Electronic address:
Rapid, sensitive, and accurate detection of heavy metal ions is significant for human health and ecological security. Herein, a novel single-stranded DNA with poly(thymidine) tail is tactfully designed as template to synthesize dual-emission silver nanoclusters (ssDNA-AgNCs). The obtained AgNCs simultaneously emit red and green fluorescence, and the red emission can be selectively quenched by Hg, meanwhile the green emission of AgNCs increases synchronously.
View Article and Find Full Text PDFSingle-Atom Iridium-doped Carbon Dots Nanozyme with High Peroxidase-Like Activity as Colorimetric Sensors for Multimodal Detection of Mercury Ions.
Small
January 2025
Chongqing Key Laboratory of Prevention and Treatment for Occupational Diseases and Poisoning, First Affiliated Hospital of Chongqing Medical and Pharmaceutical College, Chongqing, 400060, China.
Nanozyme-based colorimetric sensors are promising approaches for environmental monitoring, food safety, and medical diagnostics. However, developing novel nanozymes that exhibit high catalytic activity, good dispersion in aqueous solution, high sensitivity, selectivity, and stability is challenging. In this study, for the first time, single-atom iridium-doped carbon dot nanozymes (SA Ir-CDs) are synthesized via a simple in situ pyrolysis process.
View Article and Find Full Text PDFCan conformational flexibility influence the self-assembly behavior and sensing efficacy of fluorogenic amphiphiles? A case study with bisbenzimidazole-based probes.
Anal Methods
January 2025
Department of Chemistry, Birla Institute of Technology and Science Pilani, Hyderabad 500078, India.
In this work, we have explored the metal ion sensing properties of two bisbenzimidazole-based fluorescent probes, that differ in their conformational flexibility, in an aqueous medium. The compound with a flexible methyl spacer (1) experienced blue shifts in its absorption and emission maxima (along with a turn-off response) upon the addition of Hg ions. On the contrary, the compound with a relatively rigid structure (2) showed red shifts in both its absorption and emission maxima (along with a turn-off response) when treated with Hg under similar conditions.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!