AI Article Synopsis
- Erectile dysfunction (ED) is a common issue in men, with PDE5 inhibitors like Tadalafil helping to treat it by increasing cGMP levels in penile smooth muscle.
- Tadalafil is effective for ED caused by various factors and is known for its long-lasting effects, safety, and high patient satisfaction.
- Its benefits extend beyond physiological improvements, boosting confidence and enhancing the overall quality of sexual life, making it a strong candidate for widespread clinical use.
Article Abstract
Erectile dysfunction (ED) is a common male disease and frequently encountered in Andrology. PDE5 inhibiter can competitively inhibit the hydrolysis of cyclic guanosine monophosphate (cGMP), increase the cGMP concentration in the smooth muscle cells of the corpus cavernosum penis, and achieve the therapeutic effect on ED. Tadalafil can elevate the level of cGMP in the corpus cavernosum and effectively improve ED of various causes and degrees. Tadalafil therapy for ED, characterized by long efficacy, high safety, easy acceptance by patients and their partners, and obvious promotion of patients'self-confidence and natural experience in sexual activities, can achieve satisfactory physiological and psychological results and effectively improve the quality of patients' sexual life. Therefore tadalafil deserves an extensive clinical application in the treatment of ED.
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