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A systematic realist synthesis of digital interventions for enhancing mental health at work: contexts, mechanisms, and outcomes.
Int J Ment Health Syst
January 2025
WANT Research Team, Department of Social Psychology, Universitat Jaume I, Castelló de la Plana, Spain.
Background: Digital interventions (DIs) have emerged as promising tools for promoting mental health in the workplace. However, evidence on if, how, and under what circumstances they affect positive outcomes requires elucidation. This systematic realist review aimed to synthesize current knowledge on contexts, mechanisms, and outcomes of workplace DIs to enhance mental health at work.
View Article and Find Full Text PDFA data-driven model of disability progression in progressive multiple sclerosis.
Brain Commun
December 2024
Department of Health Sciences (DISSAL), Università di Genova, 16132 Genoa, Italy.
This study applies the Gaussian process progression model, a Bayesian data-driven disease progression model, to analyse the evolution of primary progressive multiple sclerosis. Utilizing data from 1521 primary progressive multiple sclerosis participants collected within the International Progressive Multiple Sclerosis Alliance Project, the analysis includes 18 581 longitudinal time-points (average follow-up time: 28.2 months) of disability assessments including the expanded disability status scale, symbol digit modalities, timed 25-foot-walk, 9-hole-peg test and of MRI metrics such as T1 and T2 lesion volume and normalized brain volume.
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- Sociedade Brasileira de Cirurgia Plástica - São Paulo - SP - Brasil.
Comment on "Expanding horizons in burn care: a new paradigm for General Surgeons in Brazil".
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- Associação Médica Brasileira, Diretor Científico - São Paulo - SP - Brasil.
Novel Treatment Options for Multiple Myeloma.
JCO Oncol Pract
January 2025
Fred Hutchinson Cancer Center, Seattle, WA.
Multiple myeloma (MM), the second most common hematologic malignancy in the United States, is characterized by repeated cycles of remission and relapse, with increasing resistance to treatment after each line of therapy. Despite the virtually incurable nature of MM, recent therapeutic breakthroughs have fundamentally reshaped its treatment landscape. This review explores evolving care paradigms, spanning from newly diagnosed MM to relapsed or refractory disease.
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