AI Article Synopsis
- The study investigated a new surgical sealant through animal tests and clinical trials, using various models like carotid artery anastomosis and coronary artery bypass grafting.
- The sealant effectively achieved complete hemostasis with simple interrupted sutures and maintained arterial wall thickness due to its elastomeric properties.
- In clinical trials for thoracic aortic surgery, the sealant demonstrated significantly improved hemostasis, even when patients were on heparin, leading to its approval for clinical use.
Article Abstract
For the purpose of examining the clinical applicability of a newly developed surgical sealant, animal experiments were performed, and clinical trial was followed. In animal experiments, several animal models, including carotid artery anastomosis model and coronary artery bypass grafting model were undertaken. In each model, complete hemostasis of the anastomoses using four simple interrupted sutures, was obtained. In addition, elastomeric property of the sealant prevented thinning of the arterial wall. The clinical trial performed in patients with thoracic aortic surgery showed significantly better hemostasis even under heparinized condition. Based on these excellent results, clinical usage of the sealant was approved.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!