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Reticular type parotid myoepithelial carcinoma: an intriguing variant and mimicker. | LitMetric

AI Article Synopsis

  • Myoepithelial carcinoma is a rare and malignant salivary gland tumor primarily made up of myoepithelial cells, which can grow invasively and spread to other areas.
  • A case study of a 50-year-old male with a reticular morphology highlights the risk of misdiagnosing this variant as other tumors, such as pleomorphic adenoma or adenoid cystic carcinoma.
  • The best treatment approach is complete surgical excision, while the effectiveness of radiation and chemotherapy for this type of cancer is still under investigation.

Article Abstract

Myoepithelial carcinoma, the malignant counterpart of benign myoepithelioma, is one of the rarest salivary gland neoplasms. It is composed almost exclusively of tumour cells with myoepithelial differentiation, characterized by infiltrative growth and potential for metastasis. We herein, report a case of myoepithelial carcinoma in a 50 years old male with reticular morphology. Reticular variant of myoepithelial carcinoma may be mistaken for a variety of benign and malignant epithelial and mesenchymal tumours including mixed tumour (pleomorphic adenoma), adenoid cystic carcinoma, basal cell adenoma and epithelial myoepithelial carcinoma. Complete surgical excision is the mainstay of therapy. The role of radiation therapy and chemotherapy is not yet established. Awareness of this variant is emphasized to prevent misdiagnosis.

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