Primary intratesticular rhabdomyosarcoma in pediatrics.

Indian J Urol

Department of Pathology, P.D.U. Medical College, Rajkot, Gujarat, India.

Published: January 2013

Testicular sarcomas constitute only 1-2% of all testicular tumors and are mostly associated with germ cell tumor. Primary intratesticular rhabdomyosarcoma is rare and only 14 cases have been reported in the literature till date. It should be differentiated from germ cell tumor with sarcomatous component, other intratesticular spindle-cell sarcomas and paratesticular rhabdomyosarcoma. Accurate diagnosis and early treatment is essential as it is an aggressive tumor with high metastatic potential and poor prognosis. Orchidectomy is the treatment of choice. Chemo-radiotherapy is recommended in case of recurrence and metastasis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649610PMC
http://dx.doi.org/10.4103/0970-1591.109995DOI Listing

Publication Analysis

Top Keywords

primary intratesticular
8
intratesticular rhabdomyosarcoma
8
germ cell
8
cell tumor
8
rhabdomyosarcoma pediatrics
4
pediatrics testicular
4
testicular sarcomas
4
sarcomas constitute
4
constitute 1-2%
4
1-2% testicular
4

Similar Publications

[Use of clinical ultrasound in primary care: Scrotal pathology].

Semergen

December 2024

Departamento de Ecografía, Hospital San Francisco de Asís, Madrid, España; Medicina de Familia y Comunitaria, PAC Buitrago del Lozoya, Buitrago del Lozoya, Madrid, España; Facultad de Salud, Universidad Camilo José Cela, Madrid, España; Grupo de Trabajo de Ecografía de SEMERGEN, España.

Article Synopsis
  • Ultrasound is the top non-invasive method for diagnosing testicular issues, effectively distinguishing between causes of acute pain and swelling like epididymitis and testicular torsion.
  • It can detect and analyze masses inside and outside the testicle, especially when irregularities or swelling are present.
  • Proper training and knowledge of the technique's limits improve the interpretation of ultrasound results, helping in clinical decision-making.
View Article and Find Full Text PDF

Clinical trials of intratesticular administration of nanostructured lipid carriers encapsulated alpha-mangostin: Safety and efficacy on feline reproductive health.

Theriogenology

January 2025

Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University, 39 Henri-Dunant Rd., Pathumwan, Bangkok, 10330 Thailand. Electronic address:

Surgical castration is a primary method for controlling male fertility, but it is impractical for large-scale population control of stray animals. Developing nanoparticle-mediated sterilants that induce cell apoptosis rather than necrosis is a complex and promising area of research. This study aimed to investigate the impact of intratesticular administration of alpha-mangostin encapsulated in nanostructured lipid carriers (AM-NLC) on testicular changes and any associated adverse effects over a 168-day observation period.

View Article and Find Full Text PDF

Background & Objectives: Notably, 17-hydroxy progesterone (17-OHP) (17-OHP) is a precursor for testosterone (T) synthesis, and intratesticular testosterone (ITT) is essential for spermatogenesis. Varicocele (Vx) has an estimated prevalence of 15% in the general population and 35% in those with primary infertility. We aimed to evaluate the correlation between changes of serum 17-OHP after sub-inguinal micro-varicocelectomy and improvement of semen parameters.

View Article and Find Full Text PDF

Objective: In male congenital hypogonadotropic hypogonadism (CHH), it was observed that lower dose human gonadotropic hormone (hCG) can maintain normal intratesticular testosterone levels. We propose this study to compare the low-dose hCG, follicle stimulating hormone (FSH), and Testosterone (T) [LFT Regimen] to conventional treatment to induce virilization and fertility.

Design: This open-label randomized pilot study was conducted from June 2020 to December 2021.

View Article and Find Full Text PDF
Article Synopsis
  • Tubular ectasia of the rete testis (TERT) is a benign condition characterized by multiple cysts within the testis, often found incidentally during ultrasound examinations.
  • Although TERT is generally harmless, distinguishing it from testicular tumors is crucial to prevent unnecessary surgical interventions.
  • An example case is presented of a patient who was found to have TERT in the right testis while being treated for other conditions, including cryptorchidism and hernias.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!