[Autoimmune hepatitis].

Rev Med Suisse

Service de Médecine Interne Générale, Département de Médecine Interne, Réhabilitation et Gériatrie, HUG, 1211Genève 14.

Published: April 2013

Autoimmune hepatitis is a systemic disease, difficult to diagnose due the high variability of the clinical presentation and some non specific histological features. The recent identification of additional autoantibodies used as serological markers, as well as simplified diagnostic criteria should help the primary care physician to advance with the diagnostic process. These progresses are crucial as undiagnosed and therefore untreated autoimmune hepatitis has a poor prognosis, whereas immunosuppressive therapy leads to remission in a majority of cases.

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