AI Article Synopsis
- The study examined how ethanol affects bioamines in the jejunum during different alcohol intoxication stages.
- The researchers measured levels of catecholamines, serotonin, and histamine using advanced microscopy techniques.
- They found that after 60 days of chronic alcohol use, there was an uneven increase in biogenic amines, but after 180 days, the balance was disrupted, with catecholamines becoming more dominant.
Article Abstract
We studied the effects of ethanol on bioamine-containing structures in the jejunum at different stages of alcohol intoxication. The content of catecholamines, serotonin, and histamine in enterocytes of the villus epithelium, submucosa mast cells, crypt enterocytes, and muscular layer was measured by luminescent microscopy and cytospectrofluorometry. Uneven increase of biogenic amine content was found in rats in the initial period of chronic alcohol intoxication (60 days). Further alcohol intake (up to 180 days) impaired the balance of biogenic amines; catecholamines started to prevail.
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| http://dx.doi.org/10.1007/s10517-013-2072-x | DOI Listing |
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