The mortality transition in Western Europe and the U.S. encompassed a much more complex set of conditions and experiences than earlier thought. Our research addresses the complex set of relationships among growing urban communities, family wealth, immigration and mortality in New England by examining individual-level, socio-demographic mortality correlates during the nineteenth-century mortality plateau and its early twentieth-century decline. In contrast to earlier theories that proposed a more uniform mortality transition, we offer an alternative hypothesis that focuses on the impact of family wealth and immigration on individual-level mortality during the early stages of the mortality transition in Northampton and Holyoke, Massachusetts.
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http://dx.doi.org/10.1017/S0268416012000215 | DOI Listing |
Biochem Biophys Rep
March 2025
Department of Nephrology, Pu'er People's Hospital, Pu'er, Yunnan, China.
Background: Chronic kidney disease (CKD) has become a worldwide health problem and the incidence rate and mortality of CKD have been rising. Renal fibrosis (RF) is the final common pathological feature of almost all kinds of CKD and Epithelial-mesenchymal transition (EMT) is the predominant stage of RF. β-catenin is a key component of the Wnt signaling pathway, which has been fully proven to promote EMT.
View Article and Find Full Text PDFBMJ Open Diabetes Res Care
January 2025
Department of Surgery, Woodlands Health, Singapore
Introduction: To compare the clinical outcomes and healthcare utilization of patients enrolled in the multidisciplinary Diabetic Foot in Primary and Tertiary (DEFINITE) Care program with a matched historical cohort and estimate the program's long-term cost-effectiveness using simulation.
Research Design And Methods: This study consisted of two components: a 1-year observational outcome evaluation and a long-term simulation-based cost-effectiveness analysis (CEA). We conducted an observational study to analyze 2798 patients with diabetic foot ulcers (DFUs) enrolled in the program between June 2020 and June 2021 (DEFINITE Care group) and 5462 patients with DFUs from June 2016 to December 2017 as historical controls.
Nurs Womens Health
January 2025
Cardiovascular disease (CVD) is the leading cause of mortality in women in the United States, and the physiologic changes that occur during perimenopause and menopause can increase women's risk of CVD. Physical activity levels decrease with age, but physical activity can effectively reduce both menopausal symptoms and CVD risk in women. Interventions to increase physical activity and reduce menopausal symptoms and CVD risks in women are often not comprehensive and are unsustainable due to individual contextual barriers.
View Article and Find Full Text PDFCurr Probl Cardiol
January 2025
School of Medicine and Surgery, University of Hargeis, Hargeisa 25263, Somaliland, Somalia.
Background: Cardiovascular diseases (CVDs) are leading contributors to global morbidity and mortality, with low- and middle-income countries experiencing disproportionately high burdens. In Somaliland, urbanization and lifestyle transitions have increased the prevalence of CVDs, necessitating an in-depth exploration of associated risk factors.
Objective: This study investigated the relationship between lifestyle factors and CVD prevalence among adult patients in Somaliland using data from the Hargeisa Group Hospital in 2024.
J Gastrointest Surg
January 2025
Department of Surgery, Stanford School of Medicine, Stanford CA 94305; Stanford Cancer Institute, Stanford, CA 94305. Electronic address:
Background: Fragmentation of care (FC) is healthcare provided by different providers and/or facilities. FC has been associated with inferior outcomes, yet it improves access to specialized cancer care. We aim to identify the association of fragmented gastroesophageal junction cancer (GEJ) care with survival.
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