AI Article Synopsis
- Four new organoantimony(V) complexes were created using (±)-mandelic acid and various phenyl groups (e.g., phenyl, 4-fluorophenyl).
- These complexes showed quick and low micromolar cytotoxic effects on different epithelial tumor cells in lab tests.
- They also demonstrated effective binding to CT-DNA, indicating potential for cancer treatment applications.
Article Abstract
Four novel tetranuclear organoantimony(V) complexes [R3SbL]4, in which LH = (±)-mandelic acid and R = phenyl (1), 4-fluorophenyl (2), 3-fluorophenyl (3), 3,4,5-trifluorophenyl (4), were synthesized and characterized. The complexes displayed rapid, low micromolar in vitro cytotoxicity against a range of epithelial tumour cells and efficient CT-DNA binding.
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| http://dx.doi.org/10.1039/c3dt50221j | DOI Listing |
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