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Cardiovascular Risk in Cancer Patients Treated with Immune Checkpoint Inhibitors: Challenges and Future Directions.
Eur J Prev Cardiol
June 2024
Victorian Heart Institute, Monash University, Melbourne, Australia.
Cardiovascular disease is the leading cause of non-cancer related mortality and morbidity among people living with or cured from cancer. Immune checkpoint inhibitors (ICIs) are systemic anti-cancer therapies that have revolutionised the treatment of numerous cancers, even achieving durable long-term responses among patients with metastatic disease. However, the pro-inflammatory effects of ICIs have been postulated to increase the risk of atherosclerotic cardiovascular disease (ASCVD) in cancer survivorship.
View Article and Find Full Text PDFUse of computed tomography coronary calcium score for prediction of cardiovascular events in cancer patients: a retrospective cohort analysis.
Cardiooncology
January 2024
Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Background: CT- coronary calcium score, is one of the most studied and widely available modalities in cardiovascular medicine. Coronary artery calcium score (CACS) is an established predictor of coronary artery disease. The 'standard of care' diagnostic modality to measure CACS is ECG-gated Cardiac Multi-Detector Computed Tomography.
View Article and Find Full Text PDFPerformance of the pooled cohort equations in cancer survivors: the Atherosclerosis Risk in Communities study.
J Cancer Surviv
February 2024
Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, USA.
Background: Cancer survivors may have elevated atherosclerotic cardiovascular disease (ASCVD) risk. Therefore, we tested how accurately the American College of Cardiology/American Heart Association 2013 pooled cohort equations (PCEs) predict 10-year ASCVD risk in cancer survivors.
Objectives: To estimate the calibration and discrimination of the PCEs in cancer survivors compared to non-cancer participants in the Atherosclerosis Risk in Communities (ARIC) study.
Coronary Atherosclerotic Disease and Cancer: Risk Factors and Interrelation.
Front Cardiovasc Med
April 2022
Department of Cardiology, Tangdu Hospital, The Fourth Military Medical University, Xi'an, China.
Background: In our clinical work, we found that cancer patients were susceptible to coronary atherosclerotic heart disease (CAD). However, less is known about the relationship between CAD and cancer. The present study aimed to identify the risk factors for CAD and cancer, as well as the relationship between CAD and cancer.
View Article and Find Full Text PDFStatus of dyslipidemia management and statin undertreatment in Korean cancer survivors: A Korean National Health and Nutrition Examination Survey study.
Eur J Prev Cardiol
July 2021
Endocrinology, Department of Internal Medicine, Yonsei University College of Medicine, Korea.
Aims: Due to improving cancer treatment results, non-cancer mortality is an important issue for cancer survivors. Cardiovascular diseases are the leading causes of death in Korea and globally. In addition to lowering the risk of cardiovascular disease, the use of statins has led to an overall reduction in cancer mortality in recent observational studies.
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