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Hepatotoxicity of statins: a real-world study based on the US Food and Drug Administration Adverse Event Reporting System database.
Front Pharmacol
January 2025
Department of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Background: Statins, as an important class of lipid-lowering drugs, play a key role in the prevention and treatment of cardiovascular diseases. However, with their widespread use in clinical practice, some adverse events have gradually emerged. In particular, the hepatotoxicity associated with statins use has become one of the clinical concerns that require sufficient attention.
View Article and Find Full Text PDFBackground: Dengue, chikungunya, and Zika are mosquito-borne diseases of major human concern. Differential diagnosis is complicated in children and adolescents by their overlapping clinical features (signs, symptoms, and complete blood count results). Few studies have directly compared the three diseases.
View Article and Find Full Text PDFChronic Kidney Disease-Associated Pruritus Burden: A Patient Survey Study.
Kidney Med
November 2024
Dermatology, Miller School of Medicine, University of Miami, Coral Gables, FL.
Rationale & Objective: Chronic kidney disease-associated pruritus (CKD-aP) is a common, underrecognized condition in patients with chronic kidney disease (CKD), especially those receiving hemodialysis (HD). The present study analyzed the clinical treatment journey and overall burden of pruritus among patients with CKD-aP.
Study Design: Cross-sectional, patient-reported online survey.
Exploring itch in hidradenitis suppurativa with lessons from atopic dermatitis and psoriasis.
J Dermatol
January 2025
Henry Ford Health Department of Dermatology, Detroit, Michigan, USA.
Itch is a prominent symptom in many cutaneous disorders, including atopic dermatitis (AD), prurigo nodularis, and psoriasis. Itch is also a common but overlooked concern in patients with hidradenitis suppurativa (HS). Currently, the mechanisms underlying itch in HS remain unclear.
View Article and Find Full Text PDFThe primary mechanisms underlying atopic dermatitis.
Tunis Med
January 2025
Dermatology department, CHU Ibn Rochd, Hassan II University, Faculty of Medicine and Pharmacy, Casablanca, Morocco.
Introduction: Atopic dermatitis (AD) is a complex skin disease frequently linked with other atopic symptoms such allergic rhinitis and asthma. The disease's history consists of persistent relapses with extreme pruritus, which lowers quality of life. AD has become a global health concern as its incidence has increased over the last few decades.
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