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Rapid molecular detection of macrolide resistance in the Mycobacterium avium complex: are we there yet? | LitMetric
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Rapid molecular detection of macrolide resistance in the Mycobacterium avium complex: are we there yet?

Sara Christianson William Grierson Joyce Wolfe Meenu K Sharma

J Clin Microbiol

National Reference Centre for Mycobacteriology, National Microbiology Laboratory Public Health Agency of Canada, Winnipeg, Manitoba, Canada.

Published: July 2013

Macrolides are an important tool in the treatment of Mycobacterium avium complex infections. Here, we evaluate the use of 23S rRNA gene sequencing for the rapid detection of macrolide resistance. Routine sequencing of the 23S rRNA gene is highly specific for macrolide resistance but lacks in sensitivity.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697665PMC
http://dx.doi.org/10.1128/JCM.00555-13DOI Listing

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