Dentinogenesis imperfecta (DI) is an inherited disorder that affects dentin and often manifests as tooth discoloration; in addition, the dentition is also extremely susceptible to wear. Treatment of DI focuses primarily on protecting affected dentin, reducing sensitivity, and improving esthetics. Routine restorative materials, such as amalgams and composites, may be used. In more severe cases, the treatment of choice is full coverage crowns, while bonding of veneers may be used to improve the esthetics of the anterior teeth. This study presents two cases of Type II DI in the same family and the management of each case. Restorative management included amalgams, composite veneers, crowns, bridges, and overdentures.
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The genetics of non-syndromic dentinogenesis imperfecta: a systematic review.
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Article Synopsis
- Osteogenesis imperfecta (OI) is a genetic connective tissue disorder leading to fragile bones, with a global occurrence of 1 in 10,000; diagnosis relies on clinical and radiological assessments.
- A study examined 91 pediatric OI patients at a national institute, revealing that most had fractures and specific physical traits like blue sclera and bowed legs; treatment typically involved bisphosphonates.
- The findings suggest the need for better OI fracture risk classification using severity scales, highlighting the importance of raising awareness and enhancing research on this rare condition.*
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