The number of anterior cruciate ligament reconstruction is increasing. Avoiding complications in anterior cruciate ligament reconstruction requires attention to surgical details. Errors during graft harvest, tunnel drilling, graft placement, graft fixation, or the presence of unrecognized pathology can lead to poor outcome. Postoperatively attention must be paid to range of motion, progress with physical therapy, and functional return to activity. Prompt recognition of complications is essential to minimize adverse patient outcomes.
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CD206+ Trem2+ macrophage accumulation in the murine knee joint after injury is associated with protection against post-traumatic osteoarthritis in MRL/MpJ mice.
PLoS One
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Lawrence Livermore National Laboratory, Physical and Life Science Directorate, Livermore, CA, United States of America.
Post-traumatic osteoarthritis (PTOA) is a painful joint disease characterized by the degradation of bone, cartilage, and other connective tissues in the joint. PTOA is initiated by trauma to joint-stabilizing tissues, such as the anterior cruciate ligament, medial meniscus, or by intra-articular fractures. In humans, ~50% of joint injuries progress to PTOA, while the rest spontaneously resolve.
View Article and Find Full Text PDFExploring Rehabilitation Protocols for Primary Anterior Cruciate Ligament Repair: Insights from a Scoping Review.
Am J Phys Med Rehabil
January 2025
Department of Physical and Rehabilitation Medicine, Hacettepe University Medical School, Ankara, Turkey.
Objectives: The primary repair of the anterior cruciate ligament (ACL) has re-emerged as a treatment for acute ruptures. While numerous studies have investigated rehabilitation after ACL reconstruction, few have focused on primary repair. We aimed to describe the rehabilitation protocols for primary ACL repair, and to identify knowledge gaps and differences between primary ACL repair and reconstruction.
View Article and Find Full Text PDFSport-specific differences in ACL injury, treatment and return to sports: Basketball.
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January 2025
Division of Neurosciences and Musculoskeletal Diseases, Department of Orthopaedic Surgery, Centre Hospitalier de Luxembourg (CHL), Luxembourg, Luxembourg.
Basketball is an intense, fast-paced game that is physically, highly demanding. Certain aspects of the game, such as the quick pivoting and cutting movements, predispose the players to serious knee injuries, including anterior cruciate ligament (ACL) tears. While an ACL tear can be a devastating condition for players, multidisciplinary management of the injury can provide the players with a reasonable chance to return to play at the pre-injury level.
View Article and Find Full Text PDFEffect of ELHLD peptide for stifle function recovery after tibial plateau leveling osteotomy in dogs.
J Vet Sci
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Department of Veterinary Surgery, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.
Importance: Patients with arthritis and ruptured cruciate ligaments typically require surgery. Following surgery, it is necessary to improve joint function in early stage.
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Adipose-derived mesenchymal stem cells combined with platelet-rich plasma are superior options for the treatment of osteoarthritis.
J Orthop Surg Res
January 2025
Department of Center of Precision Medicine, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital of Wannan Medical College), Zheshan West Road, Wuhu, 241001, Anhui, China.
Background: There is currently no definitive treatment for osteoarthritis. We examined the therapeutic effects and underlying mechanisms of platelet-rich plasma (PRP) and adipose-derived mesenchymal stem cells (ADSCs), individually or in combination, in a rat model of anterior cruciate ligament-induced degenerative osteoarthritis (OA) of the knee. This study seeks to advance clinical approaches to OA treatment.
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