AI Article Synopsis
- The study monitored 50 myasthenia gravis patients in Oman over a median of 3 years, using various diagnostic tests to assess their condition.
- Among the patients, 6 had purely ocular myasthenia, while most had generalized forms with significant bulbar involvement and a portion needing ventilatory support.
- Notably, pregnancy was generally well-tolerated, and thymectomy showed promising outcomes, with some patients achieving drug-free remission after 2 years.
Article Abstract
Objective: Clinical study and follow up of myasthenia gravis patients in Oman.
Methods: Follow up of 50 consecutive myasthenia gravis patients referred to the Sultan Qaboos University Hospital, Oman for a median period of 3 years from 1997 to 2000. We based the diagnosis on the clinical picture, repetitive nerve stimulation tests and edrophonium test. We performed a computerized tomography scan of the chest and anti-acetylcholine receptor antibodies. We reviewed the results of immuno modulatory treatment including thymectomy and compared these with other studies
Results: Of 50 patients, 6 had purely ocular myasthenia. Of the 44 with generalized myasthenia, 28 had bulbar involvement and 12 required ventilatory support. Eight out of 29 thymectomized patients had drug free remission after 2 years. There was worsening of myasthenic symptoms in only one out of 8 pregnancies and deliveries.
Conclusion: Bulbar and ventilatory involvement are more common in our series as compared with western data. Pregnancy and delivery were well tolerated.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!