Cyclosporine was suggested recently by Japanese workers to provoke central nervous systems symptoms in Behcet`s disease. We report 2 cases supporting this notion. Our aim is to draw the attention of physicians to such phenomenon as cyclosporine being frequently advocated in the treatment of uveitis due to Behcet`s disease.

Download full-text PDF

Source

Publication Analysis

Top Keywords

behcet`s disease
12
cyclosporine therapy
4
therapy provoke
4
provoke neurological
4
neurological complications
4
complications behcet`s
4
disease cyclosporine
4
cyclosporine suggested
4
suggested japanese
4
japanese workers
4

Similar Publications

Unlikely allies: Cholesterol, calcium, and cytokines drive neutrophil activation in Behcet's disease.

Cell Calcium

December 2024

Division of Rheumatology and Clinical Immunology, Departments of Medicine and Immunology, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

View Article and Find Full Text PDF

Exploring the causal relationship between inflammatory cytokines, metabolites, and Behcet's syndrome: Mendelian randomization.

Cytokine

January 2025

Department of Periodontology and Oral Mucosa, The Second Affiliated Hospital of Harbin Medical University, Harbin, China; Heilongjiang Provincial Key Laboratory of Hard Tissue Development and Regeneration, The Second Affiliated Hospital of Harbin Medical University, Harbin, China. Electronic address:

Introduction: Behcet's syndrome, as a vasculitic disease involving multiple systems, often induces oral mucosal ulcers. However, levels of inflammatory cytokines and metabolites are unknown for the probability of developing the disease. This study aims to reveal the causal relationship between the cytokines and metabolites and Behcet's syndrome through Mendelian randomization analysis.

View Article and Find Full Text PDF

Author Correction: TNF inhibitors target a mevalonate metabolite/TRPM2/calcium signaling axis in neutrophils to dampen vasculitis in Behçet's disease.

Nat Commun

January 2025

Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, The Ministry of Education Key Laboratory, Beijing, China.

View Article and Find Full Text PDF

Objective: Autoimmune diseases are systemic conditions that can have negative effects on wound healing. The objective of the present study was to investigate the efficacy of combining bone marrow-derived mesenchymal stem cells (BM-MSCs), acellular dermal matrix (ADM), split-thickness skin graft (STSG), and negative-pressure wound therapy (NPWT) for treating patients with autoimmune diseases and chronic non-healing wounds.

Methods: Thirty-four patients with autoimmune diseases and non-healing chronic wounds of the lower extremities between 2012 and 2023 were included in the study.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!