Patients with Plasmodium vivax malaria are treated with primaquine to prevent relapse infections. We report primaquine failure in a patient with 3 relapses without any possibility of re-infection. Using whole genome sequencing of the relapsing parasite isolates, we identified single nucleotide variants as candidate molecular markers of resistance.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647516 | PMC |
| http://dx.doi.org/10.3201/eid1905.121852 | DOI Listing |
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