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Resveratrol and Extra Virgin Olive Oil: Protective Agents Against Age-Related Disease.
Nutrients
December 2024
Scientific Center for Innovative Drugs, Volgograd State Medical University, Novorossiyskaya 39, 400087 Volgograd, Russia.
Resveratrol and extra virgin olive oil are both recognized for their potential protective effects against age-related diseases. This overview highlights their mechanisms of action, health benefits, and the scientific evidence supporting their roles in promoting longevity and cognitive health. A literature search was conducted.
View Article and Find Full Text PDFResveratrol polysaccharide is less cytotoxicity and inhibits UVA-, UVB-, and tertiary-butyl hydroperoxide-induced injury in human keratinocytes.
Naunyn Schmiedebergs Arch Pharmacol
January 2025
Meisterbio Co., Ltd., Okayama, Japan.
Natural stilbene compounds, such as resveratrol and pterostilbene, have been focused on owing to their diverse biological activities associated with antioxidant, anti-inflammatory, and anti-aging properties. However, their low water solubility limits their advanced applications. In this study, we investigated the protective effects of selected stilbene compounds (resveratrol, oxyresveratrol, gnetol, piceatannol, and pterostilbene) and their water-soluble derivatives (piceid, resveratrol polysaccharide, pterostilbene trisaccharide, and pterostilbene polysaccharide) against UVA-, UVB irradiation, tertiary-butyl hydroperoxide (t-BuOOH)- and hydrogen peroxide (HO)-induced injury in human epidermal cells.
View Article and Find Full Text PDFA Comprehensive Review on Current Knowledge and Future Potential of Topical Therapies in Breast Cancer Treatment.
Eur J Breast Health
January 2025
Department of Pharmaceutics, Faculty of Pharmacy, Sri Ramachandra Institute of Higher Education and Research, Chennai, India.
Breast cancer remains one of the most prevalent malignancies among women globally. Despite advances in therapeutic options, the prognosis often remains challenging. Breast cancer typically originates in the epithelial lining of glandular tissue ducts (85%) or lobules (15%).
View Article and Find Full Text PDFOxidative stress of mitophagy in neurodegenerative diseases: Mechanism and potential therapeutic targets.
Arch Biochem Biophys
December 2024
Department of Pharmacology, College of Basic Medicine, Binzhou Medical University, Yantai, China. Electronic address:
Neurodegenerative diseases are now significant chronic progressive neurological conditions that affect individuals' physical health. Oxidative stress is crucial in the development of these diseases. Among the various neurodegenerative diseases, mitochondrial damage has become a major factor in oxidative stress and disease advancement.
View Article and Find Full Text PDFPhytochemical strategies in glioblastoma therapy: Mechanisms, efficacy, and future perspectives.
Biochim Biophys Acta Mol Basis Dis
December 2024
Department of Biochemistry, School of Basic Science, Central University of Punjab, Bathinda 151401, India. Electronic address:
Glioblastoma (GBM) is foremost the most aggressive primary brain tumor, presenting extensive therapeutic challenges due to its high invasiveness, genetic complexity, and resistance to established treatments. Despite substantial advances in surgical and chemotherapeutic interventions, the median survival rate for patients is only 14.6 months, and the prognosis remains poor.
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