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| http://dx.doi.org/10.5698/1535-7597-13.2.60 | DOI Listing |
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Ex Vivo Fluorescence Confocal Microscopy Meets Innovation and Revolutionary Technology, for "Real-Time" Histological Evaluation, in Pediatric Surgical Oncology.
Children (Basel)
November 2024
Pediatric Surgery Unit, Salesi Children's Hospital, Polytechnic University of Marche, Via Filippo Corridoni, 16, 60123 Ancona, Italy.
Background And Aim: Ex vivo fluorescence confocal microscopy (FCM) systems are innovative optical imaging tools that create virtual high-resolution histological images without any standard tissue processing, either freezing or fixing in formalin and embedding in paraffin. These systems have opened an era that would revolutionize pathological examination by providing rapid, real-time assessments across various pathology subspecialties, potentially replacing conventional methods that are tissue- and time-consuming. This study aimed to present the first utilization of FCM in pediatric surgical oncology, focusing on assessing the benefits, particularly in facilitating rapid and accurate diagnosis.
View Article and Find Full Text PDFDiagnostic and Management Challenges in Interferon-γ Release Assay-Positive Patient with Sarcoid Panuveitis from a Non-Endemic Tuberculosis Region.
Ocul Immunol Inflamm
January 2025
Eye Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Purpose: To report a case of biopsy-proven sarcoidosis in a patient with panuveitis and a positive interferon-gamma release assay (IGRA) from a non-endemic tuberculosis (TB) country.
Methods: Case report.
Results: A 26-year-old male from the United Arab Emirates (UAE) presented with granulomatous panuveitis characterized by mutton-fat keratic precipitates, anterior chamber and vitreous cells, and retinal vasculitis.
Trends in Retraction of Orthopaedic Research Articles.
J Bone Joint Surg Am
December 2024
Department of Orthopaedics and Physical Performance, University of Rochester Medical Center, Rochester, New York.
Background: Despite the use of in-depth peer-review processes, there occasionally are issues with published manuscripts that require retraction. The purpose of the present study was to explore the reasons for the retraction of orthopaedic research articles, with consideration of the journal impact factor and the orthopaedic subspecialty.
Methods: In 2023, a database search was conducted for retracted papers written in the English language in the orthopaedic literature.
A consensus definition of creativity in surgery: A Delphi study protocol.
PLoS One
December 2024
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
Article Synopsis
- Clear definitions of creativity are crucial in scientific fields, especially in complex domains like surgery, where creativity can enhance problem-solving and innovation.* -
- The study aims to establish a consensus definition of creativity in surgery through the insights of experienced surgeons and existing literature, addressing the unique challenges of the profession.* -
- Methods include focus group discussions to explore surgeons' perceptions, rating existing definitions, and considering essential components of creativity beyond novelty and effectiveness.*
Bibliometric analysis of the top 100 most cited articles on the immunotherapy for glioblastoma.
Childs Nerv Syst
December 2024
Department of Neurosurgery, The First Affiliated Hospital of Gannan Medical University, West Jinling Road, Ganzhou, 341000, Jiangxi Province, China.
Article Synopsis
- - The study conducts a bibliometric analysis of the top 100 most cited articles on immunotherapy for glioblastoma, detailing trends in citation rates and authorship from 2000 to 2021.
- - Key findings include a peak publication year of 2017-2018, a majority of articles originating from the USA, and clinical cancer research as the leading journal, with certain authors showing significant contributions.
- - Results indicate that newer articles tend to have higher citation rates, more authors involved, and greater collaboration among institutions, highlighting an active and evolving research landscape in GBM immunotherapy.
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