Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/ajg.2013.43 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Background: The armamentarium of medical therapies to treat inflammatory bowel disease (IBD) continues to grow, which has expanded treatment options, particularly after first biologic failure. Currently, there are limited studies investigating the predictive value of first biologic primary non-response (PNR) on subsequent biologic success. Our objective was to determine if PNR to the first biologic for IBD is predictive of response to subsequent biologic therapy.
View Article and Find Full Text PDFAtypical Presentation of Small Bowel Crohn's Disease: Case Report of Musculoskeletal and Hepatic Complications Without Gastrointestinal Symptoms.
J Inflamm Res
December 2024
Department of Colorectal Surgery, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310016, People's Republic of China.
Herein, we described a case of small bowel Crohn's disease with recurrent, unexplained fevers, pain in the right lower back, hip, and groin area over 20 months. The patient did not present any gastrointestinal symptoms and colonoscopy showed no abnormalities. Imaging revealed a liver abscess and multiple lesions with pneumatosis in the muscles of the right lower back region.
View Article and Find Full Text PDFAn Update on Kawasaki Disease.
Curr Rheumatol Rep
December 2024
Division of Rheumatology, Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, RI, USA.
Purpose: To summarize advances in research on the epidemiology, pathogenesis, diagnosis, and treatment of Kawasaki Disease (KD), a systemic inflammatory illness of unknown etiology that affects children globally.
Recent Findings: The epidemiology of KD was affected by the COVID-19 pandemic and advances in molecular immunology and machine learning have enabled research into its pathogenesis. There is ongoing research into agents that can be used to intensify initial treatment and accumulating evidence supporting the use of certain rescue regimens for refractory disease over others.
Managing Crohn's Disease Postoperative Recurrence Beyond Prophylaxis: A Comprehensive Review with Meta-Analysis.
Biomedicines
October 2024
Department of Gastroenterology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Background And Aims: Postoperative recurrence in Crohn's disease remains a significant clinical challenge, with high recurrence rates despite advancements in medical therapy. This study aims to evaluate the efficacy of various treatments for managing postoperative recurrence following ileocolonic resection in Crohn's disease.
Methods: A comprehensive search of PubMed, Cochrane, and Scopus databases was performed to identify studies reporting on the therapeutic management of postoperative recurrence in Crohn's disease.
Successful Treatment of a Rare Complication of Varicella Pneumonitis in an Immunocompromised 11-Year-Old Child Using Pooled Intravenous Immunoglobulin.
Cureus
October 2024
Department of Infectious Diseases, Al Jalila Children's Specialty Hospital, Dubai, ARE.
Article Synopsis
- - Varicella-zoster virus causes chicken pox and shingles, and while usually mild in kids, it can be serious in immunocompromised individuals.
- - An 11-year-old boy on methotrexate (not typically immunosuppressive) developed a severe varicella infection that led to pneumonia.
- - He was treated with high-dose acyclovir and intravenous immunoglobulin (IVIG), which helped him recover completely thanks to their effectiveness in immunocompromised patients.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!