AI Article Synopsis
- The study investigates how Cryptosporidium andersoni LI03 infects three different types of gerbils: Lesser Egyptian, Mongolian, and Tristram's jird.
- While the Mongolian and Tristram's jird showed ability to partially eliminate the parasite, the Lesser Egyptian gerbil experienced a chronic infection with significantly higher parasite levels.
- This indicates that the Lesser Egyptian gerbil could serve as an effective laboratory model for studying long-term C. andersoni infections without requiring immunosuppressed host conditions.
Article Abstract
We describe the course of infection of Cryptosporidium andersoni LI03, originally isolated from cattle, in outbred Gerbillus gerbillus (Lesser Egyptian Gerbil), Meriones unguiculatus (Mongolian gerbil), and Meriones tristrami (Tristram's jird). While both Meriones spp. partially cleared the infection and shed a low number of oocysts (less than 15,000 oocysts per gram (OPG)), chronic infection with a mean infection intensity reaching 200,000 OPG was observed in G. gerbillus. These data suggest that G. gerbillus can be used as a laboratory model for the long-term maintenance and study of C. andersoni without the need for host immunosuppression.
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| http://dx.doi.org/10.1016/j.exppara.2013.04.007 | DOI Listing |
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