Analysis of the values of hemodynamics and the results of open biopsy of the lung in 60 patients with ventricular septal defect and high-level pulmonary hypertension, as well as the results of surgical treatment of 30 of them showed the expediency of diagnostic open biopsy of the lung in patients of the IIIb hemodynamic group, except for patients whose hemodynamic values range as follows: the ratio of general pulmonary to general peripheral resistance in more than 0.7; the ratio of pulmonary to systemic circulation is less than 1.5; the arteriovenous shunt is less than 25%, and the mean pulmonary artery pressure is above 75 mm Hg, and these hemodynamic values correspond with the morphological changes characteristic of stage IV-V after Heat-Edwards.

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