Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857917 | PMC |
| http://dx.doi.org/10.1093/europace/eut089 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Dorsoventral photobiomodulation therapy safely reduces inflammation and sensorimotor deficits in a mouse model of multiple sclerosis.
J Neuroinflammation
December 2024
Aix Marseille Univ, CNRS, INT, Inst. Neurosci. Timone, Marseille, France.
Background: Non-invasive photobiomodulation therapy (PBMT), employing specific infrared light wavelengths to stimulate biological tissues, has recently gained attention for its application to treat neurological disorders. Here, we aimed to uncover the cellular targets of PBMT and assess its potential as a therapeutic intervention for multiple sclerosis (MS).
Methods: We applied daily dorsoventral PBMT in an experimental autoimmune encephalomyelitis (EAE) mouse model, which recapitulates key features of MS, and revealed a strong positive impact of PBMT on the sensorimotor deficits.
Non-invasive Assessment of HydroQUInidine EffecT in Brugada Syndrome (QUIET BrS).
Heart Rhythm
December 2024
Faculty of Medicine and Health, University of Sydney, Australia; Department of Cardiology, Royal Prince Alfred Hospital, Australia. Electronic address:
Background: Hydroquinidine reduces arrhythmic events in patients with Brugada syndrome (BrS). The mechanism by which it exerts antiarrhythmic benefit and its electrophysiological effects on BrS substrate remain incompletely understood.
Objective: This study aimed to determine the effect of Hydroquinidine on ventricular depolarisation and repolarisation in patients with BrS in vivo.
An electrically-evoked compound action potential marker for local spiral ganglion neuron degeneration: The Failure Index.
J Neurosci
December 2024
Department of Experimental Otology, Hannover Medical School, Stadtfelddamm 34, 30625 Hannover, Germany.
Article Synopsis
- Spiral ganglion neuron (SGN) degeneration may lead to poorer hearing outcomes in cochlear implant (CI) users, but there's no existing method to locate these degenerated areas in patients.
- Research on guinea pigs showed that small cochlear micro-lesions significantly increased electrical thresholds and lowered eCAP amplitudes, with effects noticeable up to 3.5 mm away from the lesions.
- A new electrophysiological marker called the Failure Index (FI) was developed, which accurately indicates the presence and proximity of SGN degeneration and demonstrates a high classification accuracy in identifying affected areas, making it a promising tool for clinical applications.
Dynamic and quantitative assessment of quercetin for cardiac oxidative stress injury prevention using sensitive cardiomyocyte based biosensing.
Biosens Bioelectron
December 2024
Diabetes and Obesity Department, Tongde Hospital of Zhejiang Province, Hangzhou, China; Integrated Chinese and Western Medicine Department, Center for General Practice Medicine, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China. Electronic address:
Myocardial infarction is a leading cause of morbidity and mortality associated with cardiovascular diseases worldwide. Although novel medications and treatments greatly alleviate patient suffering, challenges related to prognostic limit the recovery of cardiac function. Currently, treatment with monomeric compounds displays promise in prognostic interventions for cardiac diseases.
View Article and Find Full Text PDFSensory Entrained TMS (seTMS) enhances motor cortex excitability.
bioRxiv
November 2024
Department of Psychiatry and Behavioral Sciences, Stanford University Medical Center, 401 Quarry Road, Stanford, CA, 94305, USA.
Transcranial magnetic stimulation (TMS) applied to the motor cortex has revolutionized the study of motor physiology in humans. Despite this, TMS-evoked electrophysiological responses show significant variability, due in part to inconsistencies between TMS pulse timing and ongoing brain oscillations. Variable responses to TMS limit mechanistic insights and clinical efficacy, necessitating the development of methods to precisely coordinate the timing of TMS pulses to the phase of relevant oscillatory activity.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!