AI Article Synopsis

  • The study aimed to investigate how antidepressants affect sexual dysfunction in individuals with depression, focusing on both males and females.
  • Researchers compared three groups: drug-free depressed patients, medicated depressed patients, and healthy volunteers, using a specific questionnaire to evaluate sexual function.
  • Findings indicated that drug-free depressed females and medicated depressed males experienced more sexual dysfunction than healthy controls, highlighting differing impacts of depression and antidepressants on sexual function between genders.

Article Abstract

Objective: Sexual dysfunction accompanied by depression may be altered by antidepressants. The effects of antidepressants on sexual dysfunction among males and females remain to be investigated.

Methods: Three groups of subjects, drug-free patients with depression (N=125), medicated patients with depression (N=145) and healthy volunteers (N=255), were recruited. A Chinese version of the Changes in Sexual Functioning Questionnaire was employed to assess sexual function as the primary outcome.

Results: Drug-free depressed females and medicated depressed males had more sexual dysfunction than healthy controls. The desire for sexual behaviors among healthy females and medicated depressed females was higher than that of drug-free depressed females.

Conclusion: Depression and antidepressants may have different impacts on the sexual function of males and females.

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Source
http://dx.doi.org/10.1016/j.genhosppsych.2013.03.015DOI Listing

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