Precise modelling of the proximal femur can be used for detecting and planning corrective surgery for subjects with deformed femurs using robotic technology or navigation systems. In this study, the proximal femoral geometry has been modelled mathematically. It is hypothesised that it is possible to fit a quadratic surface or combinations of them onto different bone surfaces with a relatively good fit. Forty-six computed tomography datasets of normal proximal femora were segmented. A least-squares fitting algorithm was used to fit a quadratic surface on the femoral head and neck such that the sum of distances between a set of points on the femoral neck and the quadratic surface was minimised. Furthermore, the position of the head-neck articular margin was also measured. The femoral neck was found to be represented as a good fit to a hyperboloid with an average root mean-squared error of 1.0 ± 0.13 mm while the shape of the femoral articular margin was a reproducible sinusoidal wave form with two peaks. The mathematical description in this study can be used for planning corrective surgery for subjects with cam-type femoroacetabular impingement.
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Front Robot AI
December 2024
School of Mechanical Engineering, Zhejiang Sci-Tech University, Hangzhou, Zhejiang, China.
To address the problems of the labeling curved surfaces vegetable with long label, such as the label wrinkled and the easy detachment, a cam-elliptical gear combined labeling mechanism with an improved hypocycloid trajectory is proposed. Provide the process of the mechanism, and establish a kinematic model of the mechanism. In order to improve the motion performances of the cam-elliptical gear combined labeling mechanism and avoid labels damage, the NSGA-II algorithm is used to optimize the parameters of the mechanism, resulting in 80 sets of Pareto solutions.
View Article and Find Full Text PDFSci Rep
December 2024
Environmental Health Science and Research Bureau, Health Canada, Vancouver, BC, Canada, Ottawa, ON, Canada.
Few studies have examined the association between air pollution and the trajectory of global health status measures related to the functional impacts of chronic disease. To address this gap, we examined the trajectory of the Health Utilities Index (HUI) over 17 years of follow-up among Canadian National Population Health Survey (NPHS) participants. Annual average nitrogen dioxide (NO) exposures from a national land use regression surface were mapped to 15,631 NPHS participants at their place of residence provided at each follow-up.
View Article and Find Full Text PDFFront Microbiol
December 2024
Medical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran.
This study aimed to screen native methionine gamma-lyase (L-methioninase) producing bacteria from soil samples and optimize the culture media for enhanced enzyme production using statistical design. Three bacteria, were identified as novel L-methioninase producers, which alternative source of L-methioninase for cancer treatment could be utilized alongside other therapeutic agents. The bacteria were isolated from various garden soils and cultured on a modified M9 medium and screened by Nessler reagent.
View Article and Find Full Text PDFHeliyon
December 2024
Department of Agricultural and Biosystems Engineering, Jomo Kenyatta University of Agriculture and Technology, P.O. Box 62000-00200, Nairobi, Kenya.
Fuelwood is the primary source of heat energy for tea processing, but its availability is declining due to population growth and logging restrictions. This study aimed to optimize the economics of biomass fuel mixtures for tea processing boilers by integrating macadamia nutshells as a supplementary fuelwood. The objective was to develop a cost-effective fuel mix strategy using Response Surface Methodology (RSM) and MATLAB simulations.
View Article and Find Full Text PDFFront Pharmacol
December 2024
School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Background And Aim: (Oliv.) Diels (Danggui, DG), exhibits potential in myocardial infarction (MI) treatment. However, research on its synergistic combinations for cardioprotective effects has been limited owing to inadequate approaches.
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